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Home Antibody All anti-C1QTNF1 antibodies

Anti-C1QTNF1 Antibody

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA306229
  • Rabbit Polyclonal CTRP1 Antibody
  • FREE positive control: HEK293T cell transient overexpression lysate (LC429769) , 20ug
100ug $325 3-7 Days
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WB(1)
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Also for C1QTNF1 (NM_030968)
cDNA Clone shRNA/siRNA Lysate Protein Request Antibody

OriGene Data

ImmunogenCTRP1 (IN) antibody was raised against a 16 amino acid peptide from near the center of human CTRP1.
Clone Name IsotypeIgG
Species ReactivityHuman, Mouse Concentration1ug/ul
Guaranteed Application *WB Suggested DilutionsWB: 1 ug/ml
BufferPBS containing 0.02% sodium azide.
Purification Affinity chromatography purified via peptide column

Reference Data

Target NameHomo sapiens C1q and tumor necrosis factor related protein 1 (C1QTNF1), transcript variant 1
Alternative NameCTRP1; GIP; ZSIG37
Database LinkNP_112230
FunctionAdipose tissue of an organism plays a major role in regulating physiologic and pathologic processes such as metabolism and immunity by producing and secreting a variety of bioactive molecules termed adipokines (reviewed in 1). One highly conserved family of adipokines is adiponectin/ACRP30 and its structural and functional paralogs, the C1q/tumor necrosis factor-?-related proteins (CTRPs) 1-7 (2). Unlike adiponectin, which is expressed exclusively by differentiated adipocytes, the CTRPs are expressed in a wide variety of tissues (3). These proteins are thought to act mainly on liver and muscle tissue to control glucose and lipid metabolism. An analysis of the crystal structure of adiponectin revealed a structural and evolutionary link between TNF and C1q-containing proteins, suggesting that these proteins arose from a common ancestral innate immunity gene (4). In obese (ob/ob) mice, RT-PCR analysis showed that mCTRP1 transcripts are seen at substantially higher levels in adipose tissues compared to those of normal mice (3).
Related Pathway

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WB Image
Western blot analysis of CTRP1 in MDA-MD-361 cell lysate with CTRP1 (IN) antibody at (A) 1 and (B) 2 µg/ml.

 

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