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Home Antibody All anti-IL21 antibodies

Anti-IL21 Antibody

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA306076
  • Rabbit Polyclonal IL-21 Antibody
  • Free Sample of Positive Control: HEK293T cell transient overexpression lysate (LC411922) , 20ug
100ug 325 In Stock
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WB(1)
IF(1)
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Also for IL21 (NM_021803)
cDNA Clone shRNA/siRNA Lysate Protein Antibody

OriGene Data

ImmunogenIL-21 antibody was raised against a synthetic peptide corresponding to 15 amino acids near the center of human IL-21 precursor .
Clone Name IsotypeIgG
Species ReactivityHuman ConcentrationLot dependent; please refer to CoA along with shipment
Guaranteed Application *WB, IF Suggested DilutionsELISA, WB: 1 ug/ml, ICC: 2 ug/ml
BufferPBS containing 0.02% sodium azide.
Purification Affinity chromatography purified via peptide column

Reference Data

Target NameHomo sapiens interleukin 21 (IL21), transcript variant 1
Alternative NameCVID11; IL-21; Za11
Database LinkNP_068575
FunctionA novel cytokine was recently identified in human and mouse and designated IL-21 , which has significant homology to IL-2, IL-4, and IL-15. The receptor for IL-21 (IL-21R, also termed NILR for novel Interleukin receptor) is a new member of the class I cytokine receptor family (1,2). IL-21R forms a complex with the common cytokine receptor g chain, gc, and mediates IL-21 signaling (3,4). IL-21 and its receptor activate JAK-STAT signaling pathway. IL-21 is expressed in activated T cells, and HL-60 and THP-1 cell lines. IL-21 plays a role in the proliferation and maturation of NK, B and T cell populations.
Related Pathway
Cytokine-cytokine receptor interaction
Jak-STAT signaling pathway

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
Western blot analysis of IL-21 expression in HL-60 cell lysate in the absence (lane A) or presence of blocking peptide (lane B) with IL-21 antibody at 1 ug /ml.
IF Image
Immunocytochemistry of IL-21 in K562 cells with IL-21 antibody at 2 ug/mL.

 

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