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Home Antibody All anti-GRIK3 antibodies

Anti-GRIK3 Antibody

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Specifications Citations (1) Related Products Product Documents
SKU Description Amount Price Availability*  
TA305864
  • Goat Anti-GRIK3 / GLUR7 Antibody
  • Free Sample of Positive Control: HEK293T cell transient overexpression lysate (LC424496) , 20ug Explanation
100ug 325 In Stock
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WB(1)

OriGene Data

ImmunogenPeptide with sequence C-KIRQLPIDSDDSRP, from the internal region of the protein sequence according to NP_000822.2.
Clone Name IsotypeGoat IgG
Species ReactivityTest: Rat, Mouse. Expected from seq similarity: Human, Mouse, Rat, Dog, Cow Concentration0.5mg/ml
Guaranteed Application *WB Suggested DilutionsWB: 0.05-0.2ug/ml.
Buffer0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin
Purification Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. Aliquot and store at -20C. Minimize freezing and thawing.

Reference Data

Target NameHomo sapiens glutamate receptor, ionotropic, kainate 3 (GRIK3)
Alternative NameEAA5; GLR7; GluK3; GLUR7; GluR7a
Database LinkNP_000822
Entrez Gene 2899 Human
Entrez Gene 14807 Mouse
Entrez Gene 298521 Rat
FunctionGlutamate receptors are the predominant excitatory neurotransmitter receptors in the mammalian brain and are activated in a variety of normal neurophysiologic processes. This gene product belongs to the kainate family of glutamate receptors, which are composed of four subunits and function as ligand-activated ion channels. It is not certain if the subunit encoded by this gene is subject to RNA editing as the other 2 family members (GRIK1 and GRIK2). A Ser310Ala polymorphism has been associated with schizophrenia, and there are conflicting reports of its association with the pathogenesis of delirium tremens in alcoholics. [provided by RefSeq].
Related PathwayTransmembraneIon Channels: Glutamate ReceptorsDruggable Genome Neuroactive ligand-receptor interaction

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
TA305864(0.3ug/ml) staining of Rat Brain lysate (35ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.

 

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