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Home Antibody All anti-MAP2K5 antibodies

Anti-MAP2K5 Antibody EP648Y

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SKU Description Amount Price Availability*  
TA303667
  • Rabbit monoclonal antibody against MKK5(EP648Y)
  • Free Sample of Positive Control: HEK293T cell transient overexpression lysate (LC419128) , 20ug Explanation
100ul $325 3-7 Days
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WB(1)
IF(2)

OriGene Data

ImmunogenA synthetic peptide corresponding to residues within human MKK5 was used as an immunogen.
Clone NameEP648Y IsotypeIgG
Species ReactivityHuman (Does not react with: Mouse, Rat) ConcentrationLot dependent; please refer to CoA along with shipment
Guaranteed Application *WB, IF Suggested DilutionsWB: 1:10,000; ICC: 1:100-250
Predicted MW Explanation 49 kDa
BufferPBS 49%,Sodium azide 0.01%,Glycerol 50%,BSA 0.05%
Purification Tissue culture supernatant
Note Does not react with Mouse, Rat

Reference Data

Target NameHomo sapiens mitogen-activated protein kinase kinase 5 (MAP2K5), transcript variant 2
Alternative NameHsT17454; MAPKK5; MEK5; PRKMK5
Database LinkNP_002748
Entrez Gene 5607 Human
FunctionThe protein encoded by this gene is a dual specificity protein kinase that belongs to the MAP kinase kinase family. This kinase specifically interacts with and activates MAPK7/ERK5. This kinase itself can be phosphorylated and activated by MAP3K3/MEKK3, as well as by atypical protein kinase C isoforms (aPKCs). The signal cascade mediated by this kinase is involved in growth factor stimulated cell proliferation and muscle cell differentiation. Four alternatively spliced transcript variants of this gene encoding distinct isoforms have been described. [provided by RefSeq].
Related PathwayProtein KinaseDruggable Genome MAPK signaling pathwayGap junctionNeurotrophin signaling pathway

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

Western blot - MEK5 antibody [EP648Y]; Anti-MEK5 antibody [EP648Y] at 1/10000 dilution + HeLa cell lysate.Predicted band size : 49 kDa.Observed band size : 49 kDa.
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Immunocytochemistry/ Immunofluorescence - MEK5 antibody [EP648Y]; Immunofluorescent staining of HeLa using TA303667.
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Immunocytochemistry/ Immunofluorescence - MEK5 antibody [EP648Y]; TA303667 at 1/100 staining HeLa cells by ICC/IF. The cells were paraformaldehyde fixed and blocked with goat serum prior to incubation with the antibody for 45 minutes. An Alexa Fluor® 488 conjugated goat polyclonal antibody was used as the secondary. This antibody detects MEK5 in HeLa cells as a cytoplasmic protein.
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