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Anti-CAMK1 Antibody EP2218Y
Also for CAMK1 (NM_003656)
|A synthetic peptide corresponding to residues near the C-terminus of human CaMK1 was used as an immunogen.|
||Tissue culture supernatant
|Human (Does not react with: Mouse, Rat)
||Lot dependent; please refer to CoA along with shipment
||WB: 1:20000 - 1:50000; IP: 1:20; ICC: 1:100 - 1:250; FC: 1:10
|PBS 49%,Sodium azide 0.01%,Glycerol 50%,BSA 0.05%|
|Tissue culture supernatant
|Is unsuitable for IHC-P.
|Homo sapiens calcium/calmodulin-dependent protein kinase I (CAMK1)|
Entrez Gene 8536 Human
|Ca(+2)/calmodulin-dependent protein kinases (CaMKs) are activated upon binding of Ca(+2)/calmodulin. To gain maximal activity, CaMK I and CaMK IV can be further phosphorylated by an upstream kinase, CaMK kinase (CaMKK) (1). CaMKI is a Ca2+/calmodulin-dependent protein kinase that is widely expressed in eukaryotic cells and tissues but for which few, if any, physiological substrates are known (2). CaMKI has been shown to comprise a family of four structurally related isoforms (alpha, beta, gamma, and delta) encoded by separate genes with abundant expression in mature brain. In mouse brain, the four isoforms of CaMKI were found to exhibit distinct spatiotemporal expression during neuronal development. CaMKI may also have possible functional involvement of in the basal dendritic growth of hippocampal neurons (3) |
|Protein KinaseDruggable Genome |
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Western blot - CaMKI antibody [EP2218Y]; Anti-CaMKI antibody [EP2218Y] at 1/20000 dilution + SH-SY5Y cell lysate at 10 ug.Secondary.goat anti-rabbit, HRP labeled, at 1/2000 dilution.Predicted band size : 41 kDa.Observed band size : 41 kDa.