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Anti-CAMK1 Antibody EP2218Y
Also for CAMK1 (NM_003656)
|A synthetic peptide corresponding to residues near the C-terminus of human CaMK1 was used as an immunogen.|
||Tissue culture supernatant
||0.5~1.0 mg/ml (Lot Dependent)
||WB: 1:20000 - 1:50000; IP: 1:20; ICC: 1:100 - 1:250; FC: 1:10
|Does not react with Mouse, Rat. Is unsuitable for IHC-P.|
|PBS 49%,Sodium azide 0.01%,Glycerol 50%,BSA 0.05%
|Is unsuitable for IHC-P.
|Homo sapiens calcium/calmodulin-dependent protein kinase I (CAMK1)|
|Ca(+2)/calmodulin-dependent protein kinases (CaMKs) are activated upon binding of Ca(+2)/calmodulin. To gain maximal activity, CaMK I and CaMK IV can be further phosphorylated by an upstream kinase, CaMK kinase (CaMKK) (1). CaMKI is a Ca2+/calmodulin-dependent protein kinase that is widely expressed in eukaryotic cells and tissues but for which few, if any, physiological substrates are known (2). CaMKI has been shown to comprise a family of four structurally related isoforms (alpha, beta, gamma, and delta) encoded by separate genes with abundant expression in mature brain. In mouse brain, the four isoforms of CaMKI were found to exhibit distinct spatiotemporal expression during neuronal development. CaMKI may also have possible functional involvement of in the basal dendritic growth of hippocampal neurons (3) |
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Western blot - CaMKI antibody [EP2218Y]; Anti-CaMKI antibody [EP2218Y] at 1/20000 dilution + SH-SY5Y cell lysate at 10 µg.Secondary.goat anti-rabbit, HRP labeled, at 1/2000 dilution.Predicted band size : 41 kDa.Observed band size : 41 kDa.