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Home Antibody All anti-KLK3 antibodies

Anti-KLK3 Antibody EP1588Y


Specifications Citations Customer Reviews Product Documents
SKU Description Amount Price Availability*  
TA300883 Rabbit Monoclonal Antibody against KLK3 (Clone EP1588Y) 100ul $325 In Stock
LC419823 KLK3 HEK293T cell transient overexpression lysate (as WB positive control) 20ug $50 In Stock
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OriGene Data

ImmunogenA synthetic peptide corresponding to residues near the C-terminal of human PSA.
Clone NameEP1588Y IsotypeIgG
Species ReactivityHuman (Does not react with: Mouse, Rat) ConcentrationLot dependent; please refer to CoA along with shipment
Guaranteed Application *WB, Assay, IHC Suggested DilutionsWB: 1:10000 - 1:50000; IHC-P: 1:100 - 1:250
BufferPBS 49%,Sodium azide 0.01%,Glycerol 50%,BSA 0.05%
Purification Tissue culture supernatant
Note Is unsuitable for Flow Cyt or IP.

Reference Data

Target NameHomo sapiens kallikrein-related peptidase 3 (KLK3), transcript variant 1
Alternative NameAPS; hK3; KLK2A1; PSA
Database LinkNP_001639
Entrez Gene 354 Human
FunctionProstate-specific antigen (PSA, Kallikrein-3, KLK3) is a serine protease that is usually secreted from the prostate gland and presented in seminal plasma. PSA function in the liquefaction of seminal coagulum, through hydrolysis of the high molecular mass seminal vesicle protein. Its substrates includes semenogelin I & II, fibronectin, insulin-like growth factor binding protein 3 (IGBP3), and laminin (1). Highly expressed by normal and malignant prostate cancer cells, PSA has been implicated in the growth, invasion, and metastasis of prostate cancer cells (2). Therefore, PSA is widely used as a diagnostic marker for prostate cancer. Recently, PSA has been suggested as an endothelial cell-specific inhibitor of angiogenesis (3).
Related PathwaySecreted ProteinProteaseDruggable Genome Pathways in cancerProstate cancer

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
Western blot - Prostate Specific Antigen antibody [EP1588Y]; Anti-Prostate Specific Antigen antibody [EP1588Y] at 1/10000 dilution + human prostate carcinoma tissue lysate at 10 ug.Secondary.HRP labelled goat anti-rabbit at 1/2000 dilution.Predicted band size : 29 kDa.Observed band size : 34 kDa .

Assay Image
Other-Anti-Prostate Specific Antigen antibody [EP1588Y](TA300883); Equilibrium disassociation constant (KD)..

IHC Image
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Prostate Specific Antigen antibody [EP1588Y]; TA300883, at 1/100 dilution, staining Prostate Specific Antigen in paraffin-embedded human prostate carcinoma tissue by immunohistochemistry.


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