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Home Antibody All anti-CD8A antibodies

Anti-CD8A Antibody EP1150Y

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA300779
  • Rabbit Monoclonal Antibody against CD8A (Clone EP1150Y)
  • Free Sample of Positive Control: HEK293T cell transient overexpression lysate (LC403530) , 20ug Explanation
100ul 325 In Stock
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WB(1)
IHC(1)
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Also for CD8A (NM_171827)
cDNA Clone shRNA/siRNA Lysate Protein Antibody

OriGene Data

ImmunogenA synthetic peptide corresponding to residues near the C-terminus of human CD8 was used as an immunogen
Clone NameEP1150Y IsotypeTissue culture supernatant
Species ReactivityHuman (Does not react with: Mouse, Rat) ConcentrationLot dependent; please refer to CoA along with shipment
Guaranteed Application *WB, IHC Suggested DilutionsWB: 1:1000 - 1:10000; IHC-P: 1:250 - 1:500; ICC: 1:50 - 1:100
BufferDoes not react with Mouse, Rat. Is unsuitable for Flow Cyt or IP.
Purification PBS 49%,Sodium azide 0.01%,Glycerol 50%,BSA 0.05%
Note Is unsuitable for Flow Cyt or IP.

Reference Data

Target NameHomo sapiens CD8a molecule (CD8A), transcript variant 2
Alternative NameCD8; Leu2; MAL; p32
Database LinkNP_741969
Entrez Gene 925 Human
FunctionThe T cell coreceptor CD8 is a cell-surface glycoprotein expressed either as a disulfide-linked homodimer of two CD8alpha monomers, or a heterodimer of CD8alpha and CD8beta. These receptors interact with ligands, such as major histocompatibility complex (MHC) class I, on the outside of the cell, with proteins inside the cell, such as the tyrosine kinase p56lck, and possibly with proteins on the same cell-surface (1). CD8 plays an important role in T cell development in the thymus and T cell activation in the periphery (2).
Related PathwaySecreted ProteinES Cell Differentiation/IPSTransmembraneAdult stem cellsDruggable Genome Cell adhesion molecules (CAMs)Antigen processing and presentationHematopoietic cell lineageT cell receptor signaling pathwayPrimary immunodeficiency

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
Western blot - CD8 antibody [EP1150Y]; Anti-CD8 antibody [EP1150Y] at 1/1000 dilution + THP-1 lysate at 10 ug.Predicted band size : 26 kDa.
IHC Image
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - CD8 antibody [EP1150Y]; Human tonsil with TA300779 at 1/250 dilution.

 

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