3' UTR Citations

OriGene products have been used extensively by scientists worldwide to improve their research efficiency. For your reference, we have collected a representation of citations for selected OriGene products and posted them at this site.

Search citations by gene symbols or target names

Here are some of the recent papers making use of OriGene products by fellow researchers.

Target Research Paper Journal Product SKU
AAT Isolation and identification of cell-specific microRNAs targeting a messenger RNA using a biotinylated anti-sense oligonucleotide capture affinity technique Nucleic Acids Res., Apr 2013; 41: e71. 3' UTR SC216088
ABCG1 Pro-apoptotic miRNA-128-2 modulates ABCA1, ABCG1 and RXRa expression and cholesterol homeostasis Cell Death and Disease 4, e780 doi:10.1038/cddis.2013.301 3' UTR SC210681
ACACA MicroRNA-195 inhibits proliferation, invasion and metastasis in breast cancer cells by targeting FASN, HMGCR, ACACA and CYP27B1 Sci Rep Dec 2015 3' UTR SC218496
ACOT7 Novel miRNA-31 and miRNA-200a-Mediated Regulation of Retinoblastoma Proliferation PLoS ONE Sep 2015 3' UTR SC204439
ADAM12 ADAM12-L is a direct target of the miR-29 and miR-200 families in breast cancer BMC cancer Mar 2015 3' UTR SC220027
ADAM12 MULTIPLE ISOFORMS OF ADAM12 IN BREAST CANCER: DIFFERENTIAL REGULATION OF EXPRESSION AND UNIQUE ROLES IN CANCER PROGRESSION Thesis Jul 2014 3' UTR SC220027
ATF6 PERK regulated miR-424(322)-503 cluster fine-tunes activation of IRE1 and ATF6 during Unfolded Protein Response Sci Rep Dec 2015 3' UTR SC205479
ATF6 miRNA-221 is elevated in cystic fibrosis airway epithelial cells and regulates expression of ATF6 Molecular and Cellular Pediatrics Jul 2015 3' UTR SC205479
ATG5 MiR-216a: a link between endothelial dysfunction and autophagy Cell Death Dis, Jan 2014. 3' UTR SC217570
ATP2A2 miR-25 Tough Decoy enhances cardiac function in heart failure Molecular Therapy 2017 3' UTR SC210032
ATP6AP2 MicroRNA-152 represses VEGF and TGFß1 expressions through post-transcriptional inhibition of (Pro)renin receptor in human retinal endothelial cells Mol. Vis. Mar 2015 3' UTR SC210837
AURKA Epigenetic silencing of miR-137 contributes to early colorectal carcinogenesis by impaired Aurora-A inhibition Oncotarget 2016 3' UTR SC209773
AXL The Axl-Regulating Tumor Suppressor miR-34a Is Increased in ccRCC but Does Not Correlate with Axl mRNA or Axl Protein Levels PLoS ONE Aug 2015 3' UTR SC216808
BECN1 mda-7/IL-24 Mediates Cancer Cell-Specific Death via Regulation of miR-221 and the Beclin-1 Axis Cancer Res 2017 3' UTR SC208275
BECN1 MiR-216a: a link between endothelial dysfunction and autophagy Cell Death Dis, Jan 2014. 3' UTR SC208275
BMI1 Hinokitiol up-regulates miR-494-3p to suppress BMI1 expression and inhibits self-renewal of breast cancer stem/progenitor cells Oncotarget 2017 3' UTR SC217171
BMI1 miR-494-3p Induces Cellular Senescence and Enhances Radiosensitivity in Human Oral Squamous Carcinoma Cells Int J Mol Sci 2016 3' UTR SC217171
BMI1 MicroRNA-128 coordinately targets Polycomb Repressor Complexes in glioma stem cells Neuro Oncology, Jun 2013; 10.1093/neuonc/not055. 3' UTR SC217171
C17ORF37 MicroRNA-940 suppresses prostate cancer migration and invasion by regulating MIEN1 Mol. Cancer Nov 2014 3' UTR SC205280
CASP9 Novel Anti-Apoptotic MicroRNAs 582-5p and 363 Promote Human Glioblastoma Stem Cell Survival via Direct Inhibition of Caspase 3, Caspase 9, and Bim PLoS ONE May 2014 3' UTR SC208909
CCL2 miR-98 and let-7g* protect the blood-brain barrier under neuroinflammatory conditions J. Cereb. Blood Flow Metab. Jul 2015 3' UTR SC205217
CCL5 miR-98 and let-7g* protect the blood-brain barrier under neuroinflammatory conditions J. Cereb. Blood Flow Metab. Jul 2015 3' UTR SC210875
CD163 MicroRNA networks associated with active systemic juvenile idiopathic arthritis regulate CD163 expression and anti-inflammatory functions in macrophages through two distinct mechanisms J. Leukoc. Biol. 2018 3' UTR SC208301
CDC7 p53 controls CDC7 levels to reinforce G1 cell cycle arrest upon genotoxic stress Cell Cycle 2016 3' UTR SC214002
CDKN1A Barrier Function of the Repaired Skin Is Disrupted Following Arrest of Dicer in Keratinocytes Mol. Ther. Apr 2015 3' UTR SC215244
CDKN1B In Vitro and In Vivo Activity of a Novel Locked Nucleic Acid (LNA)-Inhibitor-miR-221 against Multiple Myeloma Cells PLOS ONE, Feb 2014. 3' UTR SC214055
CFTR Regulation of Cystic Fibrosis Transmembrane Conductance Regulator by MicroRNA-145, -223, and -494 Is Altered in F508 Cystic Fibrosis Airway Epithelium J. Immunol., Apr 2013; 190: 3354 - 3362. 3' UTR SC215270
CTCFL miR-193a-3p interaction with HMGB1 downregulates human endothelial cell proliferation and migration Sci Rep 2017 3' UTR SC214474
CTGF MicroRNA-26a inhibits TGF-ß-induced extracellular matrix protein expression in podocytes by targeting CTGF and is downregulated in diabetic nephropathy Diabetologia Jun 2015 3' UTR SC212423
custom cJUN microRNA-200b modulates microglia-mediated neuroinflammation via the cJun/MAPK pathway J. Neurochem. April 2014 3' UTR
custom cJUN microRNA-200b modulates microglia-mediated neuroinflammation via the cJun/MAPK pathway J. Neurochem. April 2014 3' UTR
CYP27B1 MicroRNA-195 inhibits proliferation, invasion and metastasis in breast cancer cells by targeting FASN, HMGCR, ACACA and CYP27B1 Sci Rep Dec 2015 3' UTR SC210195
DEPDC6 microRNA-181a downregulates deptor for TGFβ-induced glomerular mesangial cell hypertrophy and matrix protein expression Exp. Cell Res. 2018 3' UTR SC213241
EGLN2 Hypoxic lung cancer-secreted exosomal miR-23a increased angiogenesis and vascular permeability by targeting prolyl hydroxylase and tight junction protein ZO-1 Oncogene 2017 3' UTR SC207831
FAK MiR-138 and MiR-135 Directly Target Focal Adhesion Kinase, Inhibit Cell Invasion, and Increase Sensitivity to Chemotherapy in Cancer Cells Anticancer Agents Med Chem, Jan 2014. 3' UTR SC212185
FASN MicroRNA-195 inhibits proliferation, invasion and metastasis in breast cancer cells by targeting FASN, HMGCR, ACACA and CYP27B1 Sci Rep Dec 2015 3' UTR SC210244
FOXJ3 MicroRNA-494 regulates mitochondrial biogenesis in skeletal muscle through mitochondrial transcription factor A and Forkhead box j3 Am J Physiol Endocrinol Metab, Dec 2012; 303: E1419 - E1427. 3' UTR SC220419
Foxo4 Foxo4- and Stat3-dependent IL-10 production by progranulin in regulatory T cells restrains inflammatory arthritis FASEB J 2016 3' UTR SC214742
FOXO4 Down-Regulation of miR-23b Induces Phenotypic Switching of Vascular Smooth Muscle Cells in vitro and in vivo Cardiovasc. Res. May 2015 3' UTR SC214742
GAPDH PKCe Promotes HuD-Mediated Neprilysin mRNA Stability and Enhances Neprilysin-Induced Aß Degradation in Brain Neurons PLoS ONE May 2014 3' UTR SC202241
GJA1 Kruppel-like factor 4 signals through microRNA-206 to promote tumor initiation and cell survival Oncogenesis Jun 2015 3' UTR SC216210
GLRB Inhibition of miR-203 Reduces Spontaneous Recurrent Seizures in Mice Mol. Neurobiol. May 2016 3' UTR SC215897
GPX1 Oscillating glucose induces microRNA-185 and impairs an efficient antioxidant response in human endothelial cells Cardiovasc Diabetol May 2016 3' UTR SC202736
HBG1 Stable expression of miR-34a mediates fetal hemoglobin induction in K562 cells Exp. Biol. Med. (Maywood) Mar 2016 3' UTR SC200439
HBG2 Stable expression of miR-34a mediates fetal hemoglobin induction in K562 cells Exp. Biol. Med. (Maywood) Mar 2016 3' UTR SC200430
HMGCR MicroRNA-195 inhibits proliferation, invasion and metastasis in breast cancer cells by targeting FASN, HMGCR, ACACA and CYP27B1 Sci Rep Dec 2015 3' UTR SC216360
HPGD ?-3 polyunsaturated fatty acids upregulate 15-PGDH expression in cholangiocarcinoma cells by inhibiting miR-26a/b expression Cancer Res. Feb 2015 3' UTR SC216485
HYOU1 miR-193a-3p interaction with HMGB1 downregulates human endothelial cell proliferation and migration Sci Rep 2017 3' UTR SC214544
IL8 Expression of miR-93 and IL-8 During Pseudomonas aeruginosa Mediated Induction of Pro-Inflammatory Responses Am. J. Respir. Cell Mol. Biol., Jan 2014. 3' UTR SC213557
IRAK4 Regulation of TLR2-Mediated Tolerance and Cross-Tolerance through IRAK4 Modulation by miR-132 and miR-212 J. Immunol., Feb 2013; 190: 1250 - 1263. 3' UTR SC219805
LTA4H Self-Limited versus Delayed Resolution of Acute Inflammation: Temporal Regulation of Pro-Resolving Mediators and MicroRNA Scientific Reports 2, doi:10.1038/srep00639 3' UTR SC201507
MAPK1 MicroRNA Regulation of Mitogenic Signaling Networks in the Human Placenta J. Biol. Chem. July 2014 3' UTR SC201852
MET An integrated genomic analysis of papillary renal cell carcinoma type 1 uncovers the role of focal adhesion and extracellular matrix pathways Molecular Oncology May 2015 3' UTR SC218300
miR-27b MicroRNA-27b Targets Gremlin 1 to Modulate Fibrotic Responses in Pulmonary Cells J. Cell. Biochem. Mar 2014 3' UTR SC400303
MIR371 SMAR1 binds to T(C/G) repeat and inhibits tumor progression by regulating miR-371-373 cluster. Sci Rep 2016 3' UTR SC400367
MIR372 SMAR1 binds to T(C/G) repeat and inhibits tumor progression by regulating miR-371-373 cluster. Sci Rep 2016 3' UTR SC400368
MIR373 SMAR1 binds to T(C/G) repeat and inhibits tumor progression by regulating miR-371-373 cluster. Sci Rep 2016 3' UTR SC400369
MIRLET7c A sesquiterpene lactone antrocin from Antrodia camphorata negatively modulates JAK2/STAT3 signaling via microRNA let-7c and induces apoptosis in lung cancer cells Carcinogenesis, Aug 2013; 10.1093/carcin/bgt255. 3' UTR SC400005
MSH2 Helicobacter pylori infection modulates the expression of miRNAs associated with DNA mismatch repair pathway Mol. Carcinog. 2016 3' UTR SC203467
MSH2 Helicobacter pylori infection modulates the expression of miRNAs associated with DNA mismatch repair pathway Mol. Carcinog. 2016 3' UTR SC203467
MSH3 Helicobacter pylori infection modulates the expression of miRNAs associated with DNA mismatch repair pathway Mol. Carcinog. 2016 3' UTR SC211522
MSH3 Helicobacter pylori infection modulates the expression of miRNAs associated with DNA mismatch repair pathway Mol. Carcinog. 2016 3' UTR SC211522
MTA1 The E3 ligase for metastasis associated 1 protein, TRIM25, is targeted by microRNA-873 in hepatocellular carcinoma Exp. Cell Res. 2018 3' UTR SC207007
MTOR An integrated genomic analysis of papillary renal cell carcinoma type 1 uncovers the role of focal adhesion and extracellular matrix pathways Molecular Oncology May 2015 3' UTR SC211383
MYB MicroRNA-150 Expression Induces Myeloid Differentiation of Human Acute Leukemia Cells and Normal Hematopoietic Progenitors PLoS One. 2013 Sep 24;8(9):e75815 3' UTR SC213071
MYC MicroRNA Regulation of Mitogenic Signaling Networks in the Human Placenta J. Biol. Chem. July 2014 3' UTR SC206606
MZF1 Let-7 microRNA controls invasion-promoting lysosomal changes via the oncogenic transcription factor myeloid zinc finger-1 Oncogenesis 2018 3' UTR SC201770
NCL Nucleolin Mediates MicroRNA-directed CSF-1 mRNA Deadenylation but Increases Translation of CSF-1 mRNA Mol. Cell. Proteomics, Jun 2013; 12: 1661 - 1677. 3' UTR SC206187
NOD2 miRNAs Affect the Expression of Innate and Adaptive Immunity Proteins in Celiac Disease Am. J. Gastroenterol. July 2014 3' UTR SC213503
NOS2 Regulation of proinflammatory genes by the circulating microRNA hsa-miR-939 Sci Rep 2016 3' UTR SC206494
NOS2 MicroRNA Regulation of Proinflammatory Response in X-linked Adrenoleukodystrophy Journal of Clinical & Cellular Immunology Jul 2015 3' UTR SC206494
NUP98 ADAR2/miR-589-3p axis controls glioblastoma cell migration/invasion Nucleic Acids Res. 2017 3' UTR SC212817
PARP1 microRNA 223 Is Upregulated in the Multistep Progression of Barrett's Esophagus and Modulates Sensitivity to Chemotherapy by Targeting PARP1 Clin. Cancer Res., Aug 2013; 19: 4067 - 4078. 3' UTR SC209859
PCBP1 MicroRNA-490 regulates lung cancer metastasis by targeting poly r(C)-binding protein 1 Tumour Biol. 2016 3' UTR SC205517
PCBP1 Poly r(C) binding protein (PCBP) 1 is a negative regulator of thyroid carcinoma Am J Transl Res 2016 3' UTR SC205517
PCBP1 Poly r(C) binding protein is post-transcriptionally repressed by MiR-490-3p to potentiate squamous cell carcinoma Tumour Biol. 2016 3' UTR SC205517
PCBP1 Poly r (C) binding protein (PCBP) 1 is a negative regulator of thyroid carcinoma American Journal of Translational Research 2016 3' UTR SC205517
PDCD4 Kruppel-like factor 4 signals through microRNA-206 to promote tumor initiation and cell survival Oncogenesis Jun 2015 3' UTR SC217111
PDIA6 Interplay Between the Oxidoreductase PDIA6 and microRNA-322 Controls the Response to Disrupted Endoplasmic Reticulum Calcium Homeostasis Sci Signal Jun 2014 3' UTR SC210773
PEBP1 Increased expression of miR-23a mediates a loss of expression in the RAF kinase inhibitor protein RKIP Cancer Research Apr 2016 3' UTR SC209990
PGF Erythropoietin mediated expression of Placenta Growth Factor is regulated via activation of hypoxia inducible factor -1a and post-transcriptionally by mir214 in Sickle Cell Disease Biochem. J. Apr 2015 3' UTR SC210960
PIK3CA MicroRNA-10a controls airway smooth muscle cell proliferation via direct targeting of the PI3 kinase pathway FASEB J., Feb 2014. 3' UTR SC204844
PIK3CG MicroRNA-204-3p inhibits lipopolysaccharide-induced cytokines in familial Mediterranean fever via the phosphoinositide 3-kinase γ pathway. Rheumatology (Oxford) 2017 3' UTR SC216338
PNPLA2 Micro RNA-124a Regulates Lipolysis via Adipose Triglyceride Lipase and Comparative Gene Identification 58 Int J Mol Sci Apr 2015 3' UTR SC205323
POLD3 Helicobacter pylori infection modulates the expression of miRNAs associated with DNA mismatch repair pathway Mol. Carcinog. 2016 3' UTR SC217193
POLD3 Helicobacter pylori infection modulates the expression of miRNAs associated with DNA mismatch repair pathway Mol. Carcinog. 2016 3' UTR SC217193
PRKRA MicroRNA-122 Inhibits the Production of Inflammatory Cytokines by Targeting the PKR Activator PACT in Human Hepatic Stellate Cells PLoS ONE Dec 2015 3' UTR SC208870
PSAP Prosaposin is a regulator of progranulin levels and oligomerization Nat Commun 2016 3' UTR SC212847
PSD95 FMRP regulates miR196a-mediated repression of HOXB8 via interaction with the AGO2 MID domain Mol Biosyst . April 2014 3' UTR SC210442
PTGR1 Novel involvement of miR-522-3p in high-mobility group box 1-induced prostaglandin reductase 1 expression and reduction of phagocytosis Biochim. Biophys. Acta 2017 3' UTR SC201488
PTGS2 Epigenetic silencing of miR-137 contributes to early colorectal carcinogenesis by impaired Aurora-A inhibition Oncotarget 2016 3' UTR SC219115
RASSF1 Excess of a Rassf1-targeting microRNA, miR-193a-3p, perturbs cell division fidelity Br. J. Cancer 2017 3' UTR SC210114
RASSF8 MicroRNA-181b promotes osteosarcoma cell proliferation, invasion and migration in vitro via targeting RASSF8 Int J Clin Exp Pathol 2016 3' UTR SC210298
RELA MicroRNA expression profiling of human blood monocyte subsets highlights functional differences Immunology Feb 2015 3' UTR SC209996
SERPINA1 miR-199a-5p Silencing Regulates the Unfolded Protein Response in COPD and a1 Antitrypsin Deficiency Am. J. Respir. Crit. Care Med. Dec 2013. 3' UTR SC216088
SHMT2 miR-615-5p prevents proliferation and migration through negatively regulating serine hydromethyltransferase 2 (SHMT2) in hepatocellular carcinoma Tumour Biol. Dec 2015 3' UTR SC207647
SLC2A4 MicroRNA-223 Expression Is Upregulated in Insulin Resistant Human Adipose Tissue Journal of Diabetes Research Jan 2015 3' UTR SC214541
SMAD7 Identification of a novel PPARß/d/miR-21-3p axis in UV-induced skin inflammation EMBO Mol Med Jun 2016 3' UTR SC215141
SMAD7 miR-1269 promotes metastasis and forms a positive feedback loop with TGF-[beta] Nature Communications Apr 2015 3' UTR SC215141
SNAI1 Extracellular vesicle-encapsulated miR-30e suppresses cholangiocarcinoma cell invasion and migration via inhibiting epithelial-mesenchymal transition Oncotarget 2018 3' UTR SC210383
SNAI1 MicroRNA-153 inhibits tumor progression in esophageal squamous cell carcinoma by targeting SNAI1 Tumour Biol. 2016 3' UTR SC210383
SOCS3 Constitutive STAT3 Phosphorylation Contributes to Skeletal Muscle Insulin Resistance in Type 2 Diabetes Diabetes, Feb 2013; 62: 457 - 465. 3' UTR SC215826
SOD2 Hepatitis C and Alcohol Exacerbate Liver Injury by Suppression of FOXO3 Am. J. Pathol. 1803-14 Nov 2013 3' UTR SC209718
SOX2 Human antigen R binding and regulation of SOX2 mRNA in human mesenchymal stem cells Mol. Pharmacol. Dec 2015 3' UTR SC212702
SOX2 Condensin confers the longitudinal rigidity of chromosomes Nat. Cell Biol. Jun 2015 3' UTR SC212702
SOX2 Therapeutic targeting of CBP/ß-catenin signaling reduces cancer stem-like population and synergistically suppresses growth of EBV-positive nasopharyngeal carcinoma cells with cisplatin Scientific reports Jan 2015 3' UTR SC212702
SPHK1 MicroRNA-1 Is Decreased by Hypoxia and Contributes to the Development of Pulmonary Vascular Remodeling via Regulation of Sphingosine Kinase 1 Am. J. Physiol. Lung Cell Mol. Physiol.2017 3' UTR SC203804
STIM1 Targeting the Ca(2+) Sensor STIM1 by Exosomal Transfer of Ebv-miR-BART13-3p is Associated with Sjögren's Syndrome. EBioMedicine 2016 3' UTR SC214586
TFAM Chromosome 21-derived hsa-miR-155-5p regulates mitochondrial biogenesis by targeting Mitochondrial Transcription Factor A (TFAM) Biochim. Biophys. Acta Apr 2015 3' UTR SC212176
TJP1 Hypoxic lung cancer-secreted exosomal miR-23a increased angiogenesis and vascular permeability by targeting prolyl hydroxylase and tight junction protein ZO-1 Oncogene 2017 3' UTR SC214630
TNF Regulation of proinflammatory genes by the circulating microRNA hsa-miR-939 Sci Rep 2016 3' UTR SC209984
TWIST1 MiR-548c impairs migration and invasion of endometrial and ovarian cancer cells via downregulation of Twist J. Exp. Clin. Cancer Res. Jan 2016 3' UTR SC209156
UCP2 Dynamic regulation of uncoupling protein 2 expression by microRNA-214 in hepatocellular carcinoma Biosci. Rep 2016 3' UTR SC204466
VEGFA Linking microsomal prostaglandin E Synthase-1/PGE-2 pathway with miR-15a and -186 expression: Novel mechanism of VEGF modulation in prostate cancer Oncotarget 2016 3' UTR SC217124
VPS4A Identification of a New Target of miR-16, Vacuolar Protein Sorting 4a PLoS ONE July 2014 3' UTR SC209710
WNT3A AurkA controls self-renewal of breast cancer-initiating cells promoting wnt3a stabilization through suppression of miR-128 Sci Rep Jun 2016 3' UTR SC216481