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Target Symbol
- CD59 (23)
- ALPHA 1 ANTITRYPSIN (20)
- NAT1 (16)
- CACNB2 (15)
- TCF7L2 (14)
- AKT1 (13)
- TGIF1 (13)
- IRF5 (12)
- ABLIM2 (11)
- BIN1 (11)
- CAMKK2 (11)
- RAD51 (11)
- WTAP (11)
- ZFYVE27 (11)
- B RAF (10)
- HMGA1 (10)
- IKZF3 (10)
- ING1 (10)
- MAP2 (10)
- MME (10)
- NF2 (10)
- PALM2AKAP2 (10)
- PRKAR1B (10)
- RUNX1T1 (10)
- SERPINA1 (10)
- SIGLEC6 (10)
- BAIAP2 (9)
- BANP (9)
- CD33 (9)
- FGFR4 (9)
- GBA (9)
- MALT1 (9)
- PPP2R2B (9)
- ABL2 (8)
- AP2B1 (8)
- CASP7 (8)
- CD10 (8)
- CDC42 (8)
- COASY (8)
- ERG (8)
- GGA1 (8)
- IMPDH1 (8)
- JNK1 (8)
- M-CSF (8)
- MBNL1 (8)
- MUTYH (8)
- NCALD (8)
- NDOR1 (8)
- NDRG2 (8)
- PAX2 (8)
- PDLIM2 (8)
- PPAR GAMMA (8)
- RGS3 (8)
- STAT1 (8)
- TGIF (8)
- ALKALINE PHOSPHATASE (7)
- ARSA (7)
- BAD (7)
- CAMK2B (7)
- CCM2 (7)
- CERKL (7)
- CSTF1 (7)
- DGKA (7)
- DYSTROPHIN (7)
- EGFR (7)
- EZH2 (7)
- FGR (7)
- FHL1 (7)
- FHL2 (7)
- FOXM1 (7)
- G PROTEIN ALPHA S (7)
- GGA3 (7)
- GRAMD2B (7)
- GRB10 (7)
- HFE (7)
- ICAM2 (7)
- IL1RA (7)
- INPP4A (7)
- ISOCITRATE DEHYDROGENASE (7)
- KALLIKREIN 11 (7)
- KAT5 (7)
- LAMC2 (7)
- NCF2 (7)
- NRG1 (7)
- NUMB (7)
- OPTN (7)
- PAX8 (7)
- PCBP2 (7)
- PDE4D (7)
- PEX5 (7)
- PICK1 (7)
- PLAUR (7)
- PTPN5 (7)
- RIBONUCLEASE INHIBITOR (7)
- STEAP3 (7)
- TPM1 (7)
- UBE2I (7)
- XRCC3 (7)
- ABAT (6)
- AIFM3 (6)
Species
Expression Hosts
Mutants
QC Levels
Families
- Druggable Genome (10912)
- Transmembrane (4701)
- Transcription Factors (2532)
- Secreted Protein (1947)
- Protein Kinase (1056)
- ES Cell Differentiation/IPS (838)
- Protease (723)
- Stem cell - Pluripotency (633)
- GPCR (292)
- Phosphatase (282)
- Adult stem cells (199)
- Ion Channels: Other (163)
- Nuclear Hormone Receptor (148)
- Embryonic stem cells (147)
- Cancer stem cells (98)
- P450 (98)
- Induced pluripotent stem cells (86)
- Ion Channels: Potassium (78)
- Stem cell relevant signaling - TGFb/BMP signaling pathway (62)
- Stem cell relevant signaling - JAK/STAT signaling pathway (60)
- Stem cell relevant signaling - Wnt Signaling pathway (44)
- Stem cell relevant signaling - DSL/Notch pathway (41)
- Ion Channels: Transient receptor potential (29)
- Ion Channels: Glutamate Receptors (23)
- Ion Channels: Cys-loop Receptors (22)
- Ion Channels: ATP Receptors (16)
- Ion Channels: Sodium (9)
- Ion Channels: Calcium (5)
- Ion Channels: Cyclic nucleotide gated (5)
Pathways
- Metabolic pathways (1820)
- Pathways in cancer (871)
- MAPK signaling pathway (651)
- Cytokine-cytokine receptor interaction (504)
- Focal adhesion (473)
- Regulation of actin cytoskeleton (448)
- Chemokine signaling pathway (402)
- Endocytosis (387)
- Neurotrophin signaling pathway (377)
- Insulin signaling pathway (336)
- Wnt signaling pathway (323)
- Jak-STAT signaling pathway (307)
- Neuroactive ligand-receptor interaction (297)
- Cell cycle (290)
- Alzheimer's disease (289)
- Calcium signaling pathway (285)
- Tight junction (283)
- ErbB signaling pathway (278)
- Natural killer cell mediated cytotoxicity (277)
- Axon guidance (272)
- T cell receptor signaling pathway (271)
- Purine metabolism (270)
- Prostate cancer (269)
- Toll-like receptor signaling pathway (261)
- Ubiquitin mediated proteolysis (261)
- Apoptosis (258)
- Leukocyte transendothelial migration (257)
- Pancreatic cancer (255)
- Progesterone-mediated oocyte maturation (254)
- Hematopoietic cell lineage (251)
- Colorectal cancer (250)
- Cell adhesion molecules (CAMs) (249)
- Huntington's disease (247)
- Oocyte meiosis (236)
- Fc gamma R-mediated phagocytosis (228)
- GnRH signaling pathway (222)
- Adherens junction (220)
- Chronic myeloid leukemia (218)
- Small cell lung cancer (209)
- Melanogenesis (207)
- Melanoma (202)
- Dilated cardiomyopathy (201)
- Fc epsilon RI signaling pathway (201)
- Lysosome (201)
- Vascular smooth muscle contraction (199)
- Renal cell carcinoma (198)
- B cell receptor signaling pathway (195)
- VEGF signaling pathway (195)
- Acute myeloid leukemia (192)
- Glioma (191)
- Hypertrophic cardiomyopathy (HCM) (190)
- TGF-beta signaling pathway (187)
- Gap junction (180)
- Adipocytokine signaling pathway (179)
- Endometrial cancer (179)
- Non-small cell lung cancer (179)
- p53 signaling pathway (178)
- PPAR signaling pathway (172)
- Complement and coagulation cascades (170)
- Arrhythmogenic right ventricular cardiomyopathy (ARVC) (162)
- NOD-like receptor signaling pathway (161)
- Spliceosome (161)
- Epithelial cell signaling in Helicobacter pylori infection (160)
- Long-term depression (159)
- Pathogenic Escherichia coli infection (159)
- RIG-I-like receptor signaling pathway (155)
- Antigen processing and presentation (154)
- Parkinson's disease (152)
- Glycolysis / Gluconeogenesis (151)
- Olfactory transduction (151)
- Pyrimidine metabolism (150)
- Long-term potentiation (144)
- Viral myocarditis (144)
- Systemic lupus erythematosus (142)
- Amyotrophic lateral sclerosis (ALS) (141)
- Bladder cancer (135)
- Arginine and proline metabolism (128)
- Phosphatidylinositol signaling system (128)
- mTOR signaling pathway (128)
- Thyroid cancer (125)
- ECM-receptor interaction (124)
- Oxidative phosphorylation (120)
- Cardiac muscle contraction (119)
- Type II diabetes mellitus (114)
- Valine (114)
- Cytosolic DNA-sensing pathway (113)
- Drug metabolism - cytochrome P450 (111)
- Metabolism of xenobiotics by cytochrome P450 (110)
- Vibrio cholerae infection (107)
- Ribosome (104)
- leucine and isoleucine degradation (104)
- Tryptophan metabolism (103)
- Inositol phosphate metabolism (101)
- Basal cell carcinoma (99)
- Glycerophospholipid metabolism (99)
- Hedgehog signaling pathway (98)
- Drug metabolism - other enzymes (97)
- Amino sugar and nucleotide sugar metabolism (96)
- Fatty acid metabolism (95)
- Glutathione metabolism (93)
- Glycerolipid metabolism (92)
- Alanine (91)
- aspartate and glutamate metabolism (91)
- Arachidonic acid metabolism (90)
- Type I diabetes mellitus (90)
- Tyrosine metabolism (89)
- Lysine degradation (88)
- Retinol metabolism (86)
- Autoimmune thyroid disease (85)
- Fructose and mannose metabolism (85)
- Notch signaling pathway (85)
- Pyruvate metabolism (85)
- RNA degradation (84)
- Proteasome (81)
- Nucleotide excision repair (79)
- Starch and sucrose metabolism (78)
- Propanoate metabolism (72)
- Base excision repair (70)
- Graft-versus-host disease (70)
- Butanoate metabolism (69)
- Prion diseases (69)
- Histidine metabolism (68)
- Allograft rejection (67)
- Cysteine and methionine metabolism (64)
- Primary immunodeficiency (64)
- Citrate cycle (TCA cycle) (62)
- Nitrogen metabolism (62)
- Sphingolipid metabolism (62)
- Androgen and estrogen metabolism (60)
- Glycine (59)
- serine and threonine metabolism (59)
- beta-Alanine metabolism (58)
- Pentose phosphate pathway (57)
- Regulation of autophagy (57)
- Taste transduction (57)
- DNA replication (55)
- Ether lipid metabolism (54)
- Linoleic acid metabolism (54)
- Porphyrin and chlorophyll metabolism (54)
- Dorso-ventral axis formation (52)
- Galactose metabolism (52)
- Maturity onset diabetes of the young (51)
- Aminoacyl-tRNA biosynthesis (49)
- Homologous recombination (49)
- Nicotinate and nicotinamide metabolism (46)
- SNARE interactions in vesicular transport (46)
- Selenoamino acid metabolism (46)
- Phenylalanine metabolism (45)
- Renin-angiotensin system (43)
- Primary bile acid biosynthesis (42)
- Biosynthesis of unsaturated fatty acids (40)
- Asthma (36)
- Basal transcription factors (36)
- Ascorbate and aldarate metabolism (35)
- Mismatch repair (35)
- Sulfur metabolism (35)
- Limonene and pinene degradation (33)
- Pantothenate and CoA biosynthesis (33)
- Glycosaminoglycan degradation (31)
- One carbon pool by folate (31)
- RNA polymerase (31)
- Riboflavin metabolism (31)
- Other glycan degradation (30)
- C21-Steroid hormone metabolism (29)
- N-Glycan biosynthesis (29)
- alpha-Linolenic acid metabolism (29)
- Glyoxylate and dicarboxylate metabolism (28)
- O-Glycan biosynthesis (28)
- Caffeine metabolism (27)
- Circadian rhythm - mammal (27)
- Pentose and glucuronate interconversions (27)
- Terpenoid backbone biosynthesis (27)
- Folate biosynthesis (25)
- Glycosphingolipid biosynthesis - lacto and neolacto series (23)
- Taurine and hypotaurine metabolism (23)
- Non-homologous end-joining (22)
- Glycosphingolipid biosynthesis - globo series (20)
- ABC transporters (19)
- leucine and isoleucine biosynthesis (19)
- Chondroitin sulfate biosynthesis (18)
- Heparan sulfate biosynthesis (18)
- Thiamine metabolism (18)
- Fatty acid elongation in mitochondria (17)
- Keratan sulfate biosynthesis (17)
- Glycosphingolipid biosynthesis - ganglio series (16)
- Steroid biosynthesis (16)
- Synthesis and degradation of ketone bodies (13)
- Cyanoamino acid metabolism (12)
- Methane metabolism (12)
- Phenylalanine (12)
- tyrosine and tryptophan biosynthesis (12)
- Fatty acid biosynthesis (10)
- Vitamin B6 metabolism (10)
- Glycosylphosphatidylinositol(GPI)-anchor biosynthesis (9)
- Lysine biosynthesis (8)
- D-Glutamine and D-glutamate metabolism (7)
- Ubiquinone and other terpenoid-quinone biosynthesis (7)
- Protein export (6)
- Biotin metabolism (3)
- D-Arginine and D-ornithine metabolism (2)
- Lipoic acid metabolism (1)
- O-Mannosyl glycan biosynthesis (1)