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KRAS (NM_004985) Human Mutant ORF Clone

RC400104

USD 300.00

In Stock

KRAS mutant (G12D), Myc-DDK-tagged ORF clone of Homo sapiens v-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog (KRAS), transcript variant b as transfection-ready DNA

Mutation	G12D
Vector	pCMV6-Entry
Tag	Myc-DDK
Mammalian Cell Selection	Neomycin

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TrueORF^®

KRAS (NM_004985) Human Mutant ORF Clone

RC400109

USD 300.00

In Stock

KRAS mutant (G12V), Myc-DDK-tagged ORF clone of Homo sapiens v-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog (KRAS), transcript variant b as transfection-ready DNA

Mutation	G12V
Vector	pCMV6-Entry
Tag	Myc-DDK
Mammalian Cell Selection	Neomycin

TrueORF^®

KRAS (NM_004985) Human Mutant ORF Clone

RC400107

USD 300.00

In Stock

KRAS mutant (G12C), Myc-DDK-tagged ORF clone of Homo sapiens v-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog (KRAS), transcript variant b as transfection-ready DNA

Mutation	G12C
Vector	pCMV6-Entry
Tag	Myc-DDK
Mammalian Cell Selection	Neomycin

TrueORF^®

KRAS (NM_004985) Human Mutant ORF Clone

RC400116

USD 450.00

In Stock

KRAS mutant (G13D), Myc-DDK-tagged ORF clone of Homo sapiens v-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog (KRAS), transcript variant b as transfection-ready DNA

Mutation	G13D
Vector	pCMV6-Entry
Tag	Myc-DDK
Mammalian Cell Selection	Neomycin

TrueORF^®

B Raf (BRAF) (NM_004333) Human Mutant ORF Clone

RC400155

USD 1,053.00

In Stock

BRAF mutant(V600E), Myc-DDK-tagged ORF clone of Homo sapiens v-raf murine sarcoma viral oncogene homolog B1 (BRAF) as transfection-ready DNA

Mutation	V600E
Vector	pCMV6-Entry
Tag	Myc-DDK
Mammalian Cell Selection	Neomycin

TrueORF^®

EGFR (NM_005228) Human Mutant ORF Clone

RC400290

USD 1,580.00

In Stock

EGFR Mutant (L858R), Myc-DDK-tagged ORF clone of Homo sapiens epidermal growth factor receptor (EGFR), transcript variant 1 as transfection-ready DNA

Mutation	L858R
Vector	pCMV6-Entry
Tag	Myc-DDK
Mammalian Cell Selection	Neomycin

TrueORF^®

p53 (TP53) (NM_000546) Human Mutant ORF Clone

RC400073

USD 686.00

In Stock

TP53 mutant (R273H), Myc-DDK-tagged ORF clone of Homo sapiens tumor protein p53 (TP53), transcript variant 1 as transfection-ready DNA

Mutation	R273H
Vector	pCMV6-AC-Myc-DDK
Tag	Myc-DDK
Mammalian Cell Selection	Neomycin

TrueORF^®

KRAS (NM_004985) Human Mutant ORF Clone

RC400106

USD 450.00

In Stock

KRAS mutant (G12R), Myc-DDK-tagged ORF clone of Homo sapiens v-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog (KRAS), transcript variant b as transfection-ready DNA

Mutation	G12R
Vector	pCMV6-Entry
Tag	Myc-DDK
Mammalian Cell Selection	Neomycin

TrueORF^®

AKT1 (NM_005163) Human Mutant ORF Clone

RC400163

USD 457.00

In Stock

AKT1 Mutant (E17K), Myc-DDK-tagged ORF clone of Homo sapiens v-akt murine thymoma viral oncogene homolog 1 (AKT1), transcript variant 1 as transfection-ready DNA

Mutation	E17K
Vector	pCMV6-Entry
Tag	Myc-DDK
Mammalian Cell Selection	Neomycin

TrueORF^®

CDK4 (NM_000075) Human Mutant ORF Clone

RC401060

USD 450.00

In Stock

CDK4 Mutant (R24C), Myc-DDK-tagged ORF clone of Homo sapiens cyclin-dependent kinase 4 (CDK4) as transfection-ready DNA

Mutation	R24C
Vector	pCMV6-Entry
Tag	Myc-DDK
Mammalian Cell Selection	Neomycin

TrueORF^®

B Raf (BRAF) (NM_004333) Human Mutant ORF Clone

RC400324

USD 1,052.00

In Stock

BRAF Mutant (G469A), Myc-DDK-tagged ORF clone of Homo sapiens v-raf murine sarcoma viral oncogene homolog B1 (BRAF) as transfection-ready DNA

Mutation	G469A
Vector	pCMV6-Entry
Tag	Myc-DDK
Mammalian Cell Selection	Neomycin

TrueORF^®

KRAS (NM_004985) Human Mutant ORF Clone

RC400105

USD 450.00

In Stock

KRAS mutant (G12S), Myc-DDK-tagged ORF clone of Homo sapiens v-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog (KRAS), transcript variant b as transfection-ready DNA

Mutation	G12S
Vector	pCMV6-Entry
Tag	Myc-DDK
Mammalian Cell Selection	Neomycin

TrueORF^®

PI 3 Kinase catalytic subunit alpha (PIK3CA) (NM_006218) Human Mutant ORF Clone

RC400346

USD 1,395.00

In Stock

PIK3CA Mutant (E542K), Myc-DDK-tagged ORF clone of Homo sapiens phosphoinositide-3-kinase, catalytic, alpha polypeptide (PIK3CA) as transfection-ready DNA

Mutation	E542K
Vector	pCMV6-Entry
Tag	Myc-DDK
Mammalian Cell Selection	Neomycin

TrueORF^®

p53 (TP53) (NM_000546) Human Mutant ORF Clone

RC400063

USD 686.00

In Stock

TP53 mutant (R248W), Myc-DDK-tagged ORF clone of Homo sapiens tumor protein p53 (TP53), transcript variant 1 as transfection-ready DNA

Mutation	R248W
Vector	pCMV6-AC-Myc-DDK
Tag	Myc-DDK
Mammalian Cell Selection	Neomycin

TrueORF^®

KRAS (NM_004985) Human Mutant ORF Clone

RC400108

USD 450.00

In Stock

KRAS mutant (G12A), Myc-DDK-tagged ORF clone of Homo sapiens v-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog (KRAS), transcript variant b as transfection-ready DNA

Mutation	G12A
Vector	pCMV6-Entry
Tag	Myc-DDK
Mammalian Cell Selection	Neomycin

TrueORF^®

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cDNA Clones

Mutant ORF Clones

Expression Plasmids

P53

EGFR

KRAS

B RAF

PI 3 KINASE CATALYTIC SUBUNIT ALPHA

CDK4

MEK1

RAF1

AKT1

HER2

JNK3

A RAF

ACTIVIN A RECEPTOR TYPE IB

ACTIVIN A RECEPTOR TYPE IC

AKT2

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IKK ALPHA

IKK BETA

JNK1

JNK2

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TGF BETA RECEPTOR II

Human

Myc-DDK

Tag Free

pCMV6-AC-Myc-DDK

pCMV6-Entry

pCMV6-XL4

pCMV6-XL5

pCMV6-XL6

Yes

Neomycin

None

Druggable Genome

Transcription Factors

Stem cell - Pluripotency

Protein Kinase

ES Cell Differentiation/IPS

Transmembrane

Adult stem cells

Cancer stem cells

Secreted Protein

Stem cell relevant signaling - JAK/STAT signaling pathway

Pathways in cancer

MAPK signaling pathway

Neurotrophin signaling pathway

Prostate cancer

Endometrial cancer

Glioma

Melanoma

Colorectal cancer

Non-small cell lung cancer

Bladder cancer

Pancreatic cancer

Chronic myeloid leukemia

Thyroid cancer

Wnt signaling pathway

Small cell lung cancer

Apoptosis

Cell cycle

ErbB signaling pathway

Basal cell carcinoma

p53 signaling pathway

Focal adhesion

Regulation of actin cytoskeleton

Amyotrophic lateral sclerosis (ALS)

Huntington's disease

Chemokine signaling pathway

GnRH signaling pathway

Insulin signaling pathway

Renal cell carcinoma

T cell receptor signaling pathway

Long-term potentiation

Gap junction

Acute myeloid leukemia

Fc epsilon RI signaling pathway

Melanogenesis

Progesterone-mediated oocyte maturation

Natural killer cell mediated cytotoxicity

Tight junction

VEGF signaling pathway

B cell receptor signaling pathway

Axon guidance

Endocytosis

Long-term depression

Adherens junction

Cytokine-cytokine receptor interaction

Calcium signaling pathway

mTOR signaling pathway

Dorso-ventral axis formation

Epithelial cell signaling in Helicobacter pylori infection

Toll-like receptor signaling pathway

Oocyte meiosis

Vascular smooth muscle contraction

Fc gamma R-mediated phagocytosis

Leukocyte transendothelial migration

Adipocytokine signaling pathway

TGF-beta signaling pathway

Type II diabetes mellitus

Jak-STAT signaling pathway

Pathogenic Escherichia coli infection

Arrhythmogenic right ventricular cardiomyopathy (ARVC)

Olfactory transduction

RIG-I-like receptor signaling pathway

NOD-like receptor signaling pathway

Hedgehog signaling pathway

Phosphatidylinositol signaling system

Prion diseases

Inositol phosphate metabolism

Citrate cycle (TCA cycle)

Glutathione metabolism

Metabolic pathways

Vibrio cholerae infection

Cytosolic DNA-sensing pathway

Primary immunodeficiency

Alzheimer's disease

Dilated cardiomyopathy

Hematopoietic cell lineage

Regulation of autophagy

Taste transduction

Ubiquitin mediated proteolysis

Circadian rhythm - mammal

Mismatch repair

Hypertrophic cardiomyopathy (HCM)

Viral myocarditis

Homologous recombination

Notch signaling pathway

Nucleotide excision repair

PPAR signaling pathway

Parkinson's disease

TrueORF

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Yes

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