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Antibodies
LGR5 mouse monoclonal antibody, clone OTI2A2
| Applications | FC, IF, IHC, IP, WB |
| Reactivities | Human, Mouse, Rat |
KEAP1 mouse monoclonal antibody, clone OTI1B4 (formerly 1B4)
| Applications | FC, IF, IHC, WB |
| Reactivities | Human, Mouse, Rat |
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Target Symbol
- MAP2K1 (203)
- PDCD1 (136)
- MAP2K3 (132)
- CTAG1B (131)
- LIPG (107)
- KLK8 (106)
- TP53 (104)
- ERCC1 (97)
- MAPK13 (88)
- CDKN2A (85)
- ERBB2 (83)
- VIM (83)
- L1CAM (82)
- PNMT (82)
- EPCAM (77)
- MDM4 (75)
- SYP (68)
- PECAM1 (67)
- CD163 (66)
- LOX (63)
- APP (62)
- CTNNB1 (61)
- BSG (60)
- GFAP (60)
- MLANA (60)
- IDO1 (59)
- PTPRE (59)
- TH (58)
- NPR3 (57)
- PSMC3 (57)
- BUB1B (56)
- SENP2 (56)
- SQSTM1 (56)
- AKT1 (55)
- CCT8L2 (55)
- MAPK7 (55)
- MIOX (55)
- MTRF1L (55)
- NME4 (55)
- PDE4A (55)
- ACAT2 (54)
- CHGA (54)
- MAPRE2 (53)
- MCL1 (53)
- CDK2 (52)
- LIMK1 (52)
- BTK (51)
- IGF2BP2 (51)
- RNF144B (51)
- TACC3 (51)
- UBE2G2 (51)
- BTN1A1 (50)
- FAHD2A (50)
- LENG1 (50)
- MMP13 (50)
- PIK3AP1 (50)
- SMS (50)
- SPG7 (50)
- VWA5A (50)
- BECN1 (49)
- CD19 (49)
- PGAM2 (49)
- CCM2 (47)
- CD80 (47)
- ERG (47)
- KRT7 (46)
- SNAP25 (46)
- ALDH1L1 (45)
- ARHGAP25 (45)
- CD1C (45)
- ELK3 (45)
- FOXI1 (45)
- GBP2 (45)
- HIBCH (45)
- HOXC11 (45)
- PARVA (45)
- PIK3R5 (45)
- SNX9 (45)
- TAL1 (45)
- ERCC4 (44)
- SAMHD1 (43)
- RASSF1 (42)
- PYCR2 (41)
- SIVA1 (41)
- ACAA2 (40)
- AFP (40)
- ARFGAP1 (40)
- ATP5F1B (40)
- CRYAB (40)
- DTYMK (40)
- DYNC1LI1 (40)
- HDAC6 (40)
- IL1A (40)
- LRATD2 (40)
- MICAL1 (40)
- NHEJ1 (40)
- POR (40)
- PRKAR2A (40)
- PRKCE (40)
- PYCR3 (40)
Reactivities
- Human (27142)
- Mouse (16727)
- Rat (14855)
- Monkey (2929)
- Dog (2286)
- Bovine (441)
- Porcine (344)
- Canine (310)
- Rabbit (228)
- Chicken (196)
- Hamster (105)
- Zebrafish (101)
- Primate (86)
- Feline (82)
- Sheep (81)
- Xenopus (64)
- Mammalian (57)
- Guinea Pig (49)
- Bakers Yeast (41)
- All Species (38)
- Goat (35)
- Equine (32)
- Drosophila (30)
- Chimpanzee (28)
- Yeast (23)
- Fish (21)
- Escherichia coli (18)
- Amphibian (17)
- Bacillus sp. (17)
- Bacteria (16)
- Rat Other (Wide Range) (16)
- Baboon (11)
- Candida (11)
- Duck (11)
- Mammal (10)
- Other (Wide Ratange) (10)
- not react with Mouse (10)
- Aspergillus (9)
- Avian (9)
- Chinese Hamster (9)
- Enterobacter (9)
- Gorilla (9)
- A. victoria (8)
- Human Mouse (8)
- Birds (6)
- Cow (6)
- Insect (6)
- Pigeon (6)
- Plant (6)
- mCherry (6)
- Bat (5)
- Frog (5)
- Jack Bean (5)
- Leuconostoc (5)
- Penicillium (5)
- Ratange) (5)
- tdTomato (5)
- (Wide (4)
- Broad (4)
- Guinea Porcine (4)
- Human Mouse Rat (4)
- Mink (4)
- Mk (4)
- Mouse (Negative) (4)
- Other (4)
- Photobacterium fischerii (4)
- Pig (4)
- Quail (4)
- Rat (Negative) (4)
- Rat. Not yet tested on other species (4)
- Rat. Other species not tested yet (4)
- Red Fluorescent (4)
- broad range (4)
- Alcaligenes (3)
- Bonito (3)
- C. elegans (3)
- CMV. Others-not known (3)
- Cucurbita (3)
- Human (Negative) (3)
- Human Rat (3)
- Hydra (3)
- Mousse (3)
- Orang-Utan (3)
- P. testosteroni (3)
- Photinus pyralis (3)
- Rat Mk (3)
- Reptiles (3)
- Schistosoma japonicum (3)
- Staphylococcus aureus (3)
- Streptococcus (3)
- Tuna (3)
- Virus (3)
- Beluga (2)
- Coral (2)
- Drosophilia (2)
- EGFP (2)
- GFP (2)
- HIV Type 1. Others-not known (2)
- Human. Other species not yet tested (2)
- Macaque (2)
- Maize (2)
- Marmoset (2)
- Mousek (2)
- Primate (Negative) (2)
- SARS-CoV-2 (2)
- Snake (2)
- Sweet Potato (2)
- V5-tagged proteins (2)
- YFP (2)
- Acetylated lysine residues (1)
- Atlantic Hagfish (Myxine glutinosa) (1)
- C.elegans (1)
- CMV (1)
- Carp (1)
- Cod (1)
- Dosophila (1)
- Drosop (1)
- Drosoph (1)
- Ferret (1)
- Fish (carp) (1)
- Fruit fly (Drosophila melanogaster) (1)
- Fungus (1)
- G (1)
- Gerbil (1)
- Guinea pig (1)
- Guinea porcine (1)
- Hamste (1)
- Horse (1)
- Horseradish Peroxidase (1)
- Horsereddish (1)
- Human (recognizes &Delta (1)
- Human: Ser23 (1)
- Human: Ser246 (1)
- Human: Ser852 (1)
- Human: Thr555 (1)
- Human: Thr693 (1)
- Human: Tyr1003 (1)
- Inverte (1)
- M (1)
- Mouse (Predicted: Chimpanzee) (1)
- Mouse. Other species not yet tested (1)
- Mouse: Ser23 (1)
- Mouse: Ser246 (1)
- Mouse: Ser847 (1)
- Mouse: Thr554 (1)
- Mouse: Thr695 (1)
- Mouse: Tyr1001 (1)
- Mustel (1)
- N-isoforms) (1)
- Other(Wide (1)
- Plasmodium berghei (1)
- Porcin (1)
- Potoroo (1)
- R (1)
- Rabbit (Negative) (1)
- Rat Monkey (1)
- Rat and Dog (1)
- Rat. Not tested in other species (1)
- Rat. Other species not yet tested (1)
- Rat: Ser23 (1)
- Rat: Ser847 (1)
- Rat: Thr694 (1)
- Rat: Tyr1004 (1)
- Red Fluorescent Protein (1)
- Rouse (1)
- Salmon (1)
- Salmonid (1)
- Scallop porcine (1)
- SimianIVE (1)
- Snail (1)
- Sole (1)
- Spiny Dogfish Shark (Squalus acanthias) (1)
- Squirrel Monkey (1)
- Staphylococcus epidermidis (1)
- Streptococcus Pyogenes (1)
- Tobacco (1)
- Tomato (1)
- Trout (1)
- Turkey (1)
- Venus (1)
- Wolffish (1)
- chlamydomonas (1)
- mOrange (1)
- mPlum (1)
- mRFP (1)
- mStrawberry and tdTomato (1)
- not Mouse (1)
- reacts against 1960 aa length myosin heavy chain (1)
- red fluorescent (1)
- var. (1)
Antibody Hosts
Knockout (KO) Validation
Conjugates
- Biotin (3628)
- HRP (3379)
- FITC (329)
- PE (69)
- TRITC (52)
- Alexa Fluor 546 (47)
- Alexa Fluor 488 (44)
- Alexa Fluor 647 (17)
- Texas Red (16)
- APC (9)
- Cy5 (8)
- AP (4)
- PE-Cy7 (3)
- APC-Cy5.5 (2)
- DyLight 488 (2)
- DyLight 594 (2)
- PE-Cy5.5 (2)
- PerCP (2)
- Rhodamine (2)
- APC-Cy7 (1)
- BIMA (1)
- DTAF (1)
- DyLight 550 (1)
- PerCP-Cy5.5 (1)
- Unconjugated (1)
Modifications
Isotypes
Clonalities
Brands
Availabilities
Citations
Families
- Druggable Genome (14175)
- Transmembrane (4744)
- Transcription Factors (3148)
- Protein Kinase (2047)
- ES Cell Differentiation/IPS (1862)
- Secreted Protein (1729)
- Stem cell - Pluripotency (953)
- Protease (846)
- Adult stem cells (334)
- GPCR (283)
- Phosphatase (259)
- Embryonic stem cells (223)
- P450 (194)
- Stem cell relevant signaling - JAK/STAT signaling pathway (166)
- Induced pluripotent stem cells (141)
- Ion Channels: Other (138)
- Cancer stem cells (137)
- Nuclear Hormone Receptor (128)
- Stem cell relevant signaling - DSL/Notch pathway (122)
- Stem cell relevant signaling - TGFb/BMP signaling pathway (77)
- Ion Channels: Potassium (48)
- Stem cell relevant signaling - Wnt Signaling pathway (42)
- Ion Channels: Glutamate Receptors (23)
- Ion Channels: Transient receptor potential (18)
- Ion Channels: ATP Receptors (4)
- Ion Channels: Cyclic nucleotide gated (4)
- Ion Channels: Cys-loop Receptors (4)
- Ion Channels: Calcium (3)
- Ion Channels: Sodium (1)
Pathways
- Metabolic pathways (2676)
- Pathways in cancer (1959)
- MAPK signaling pathway (1464)
- Focal adhesion (1106)
- Neurotrophin signaling pathway (1070)
- Prostate cancer (1027)
- Toll-like receptor signaling pathway (954)
- Pancreatic cancer (935)
- T cell receptor signaling pathway (926)
- Chronic myeloid leukemia (925)
- Progesterone-mediated oocyte maturation (898)
- Colorectal cancer (886)
- Non-small cell lung cancer (880)
- Insulin signaling pathway (877)
- ErbB signaling pathway (873)
- Fc epsilon RI signaling pathway (870)
- Regulation of actin cytoskeleton (849)
- Endometrial cancer (846)
- Melanoma (846)
- Glioma (808)
- Bladder cancer (775)
- GnRH signaling pathway (734)
- B cell receptor signaling pathway (712)
- Fc gamma R-mediated phagocytosis (709)
- Cell cycle (702)
- Acute myeloid leukemia (694)
- Chemokine signaling pathway (694)
- VEGF signaling pathway (653)
- Gap junction (651)
- Renal cell carcinoma (640)
- Apoptosis (626)
- Cell adhesion molecules (CAMs) (620)
- Natural killer cell mediated cytotoxicity (584)
- Leukocyte transendothelial migration (573)
- Thyroid cancer (565)
- Small cell lung cancer (529)
- Oocyte meiosis (528)
- p53 signaling pathway (528)
- Amyotrophic lateral sclerosis (ALS) (519)
- Jak-STAT signaling pathway (490)
- Alzheimer's disease (481)
- Wnt signaling pathway (469)
- Purine metabolism (462)
- Huntington's disease (460)
- Endocytosis (452)
- Melanogenesis (436)
- Hematopoietic cell lineage (416)
- Adherens junction (399)
- Cytokine-cytokine receptor interaction (398)
- Axon guidance (390)
- Vascular smooth muscle contraction (386)
- Long-term potentiation (381)
- Long-term depression (369)
- Prion diseases (366)
- Tight junction (360)
- Pathogenic Escherichia coli infection (352)
- Ubiquitin mediated proteolysis (350)
- Parkinson's disease (344)
- Adipocytokine signaling pathway (342)
- Type II diabetes mellitus (335)
- mTOR signaling pathway (334)
- Epithelial cell signaling in Helicobacter pylori infection (318)
- Glycolysis / Gluconeogenesis (306)
- Calcium signaling pathway (296)
- NOD-like receptor signaling pathway (291)
- Systemic lupus erythematosus (290)
- Pyrimidine metabolism (286)
- Neuroactive ligand-receptor interaction (282)
- Dorso-ventral axis formation (274)
- Primary immunodeficiency (274)
- RIG-I-like receptor signaling pathway (274)
- TGF-beta signaling pathway (257)
- Valine (256)
- Basal cell carcinoma (240)
- leucine and isoleucine degradation (240)
- Nucleotide excision repair (218)
- Arginine and proline metabolism (213)
- Tyrosine metabolism (206)
- Glycerolipid metabolism (200)
- Oxidative phosphorylation (195)
- Tryptophan metabolism (191)
- Antigen processing and presentation (187)
- Viral myocarditis (181)
- Arrhythmogenic right ventricular cardiomyopathy (ARVC) (175)
- Proteasome (173)
- Pyruvate metabolism (172)
- Drug metabolism - cytochrome P450 (166)
- Metabolism of xenobiotics by cytochrome P450 (159)
- Type I diabetes mellitus (157)
- Arachidonic acid metabolism (155)
- Fatty acid metabolism (146)
- Propanoate metabolism (145)
- Graft-versus-host disease (143)
- PPAR signaling pathway (143)
- Cytosolic DNA-sensing pathway (141)
- beta-Alanine metabolism (138)
- Hypertrophic cardiomyopathy (HCM) (134)
- Glutathione metabolism (132)
- Citrate cycle (TCA cycle) (129)
- Butanoate metabolism (128)
- Phosphatidylinositol signaling system (128)
- Regulation of autophagy (128)
- Glycine (123)
- Inositol phosphate metabolism (123)
- serine and threonine metabolism (123)
- Dilated cardiomyopathy (121)
- Fructose and mannose metabolism (121)
- Olfactory transduction (120)
- Retinol metabolism (115)
- Maturity onset diabetes of the young (114)
- Cysteine and methionine metabolism (111)
- Vibrio cholerae infection (110)
- Base excision repair (109)
- Notch signaling pathway (107)
- Complement and coagulation cascades (105)
- ECM-receptor interaction (101)
- Lysine degradation (99)
- Spliceosome (97)
- Lysosome (96)
- Pentose phosphate pathway (96)
- Amino sugar and nucleotide sugar metabolism (93)
- Linoleic acid metabolism (93)
- Terpenoid backbone biosynthesis (91)
- RNA degradation (88)
- Allograft rejection (86)
- Mismatch repair (85)
- Cardiac muscle contraction (83)
- Hedgehog signaling pathway (82)
- Autoimmune thyroid disease (77)
- DNA replication (75)
- Synthesis and degradation of ketone bodies (71)
- Ascorbate and aldarate metabolism (68)
- Drug metabolism - other enzymes (68)
- Non-homologous end-joining (65)
- One carbon pool by folate (64)
- RNA polymerase (64)
- Homologous recombination (63)
- Galactose metabolism (61)
- Histidine metabolism (61)
- Starch and sucrose metabolism (60)
- Caffeine metabolism (56)
- SNARE interactions in vesicular transport (55)
- Alanine (52)
- aspartate and glutamate metabolism (52)
- Nicotinate and nicotinamide metabolism (50)
- N-Glycan biosynthesis (45)
- Fatty acid elongation in mitochondria (42)
- Folate biosynthesis (42)
- Renin-angiotensin system (41)
- Porphyrin and chlorophyll metabolism (39)
- Sphingolipid metabolism (39)
- Nitrogen metabolism (37)
- Glyoxylate and dicarboxylate metabolism (35)
- Biosynthesis of unsaturated fatty acids (34)
- Glycosaminoglycan degradation (34)
- Primary bile acid biosynthesis (34)
- Other glycan degradation (30)
- Glycerophospholipid metabolism (29)
- Ribosome (28)
- Circadian rhythm - mammal (27)
- Sulfur metabolism (26)
- Androgen and estrogen metabolism (24)
- Basal transcription factors (24)
- Pantothenate and CoA biosynthesis (24)
- Selenoamino acid metabolism (22)
- Asthma (21)
- Methane metabolism (21)
- Phenylalanine metabolism (20)
- Glycosphingolipid biosynthesis - lacto and neolacto series (18)
- Fatty acid biosynthesis (17)
- Keratan sulfate biosynthesis (17)
- Glycosphingolipid biosynthesis - ganglio series (16)
- Vitamin B6 metabolism (16)
- leucine and isoleucine biosynthesis (16)
- Limonene and pinene degradation (14)
- Taurine and hypotaurine metabolism (14)
- Aminoacyl-tRNA biosynthesis (12)
- Taste transduction (12)
- Riboflavin metabolism (10)
- Steroid biosynthesis (10)
- ABC transporters (9)
- Pentose and glucuronate interconversions (9)
- O-Glycan biosynthesis (8)
- C21-Steroid hormone metabolism (6)
- Heparan sulfate biosynthesis (5)
- Chondroitin sulfate biosynthesis (4)
- D-Glutamine and D-glutamate metabolism (4)
- Ether lipid metabolism (2)
- Glycosylphosphatidylinositol(GPI)-anchor biosynthesis (2)
- alpha-Linolenic acid metabolism (2)
- Cyanoamino acid metabolism (1)
- D-Arginine and D-ornithine metabolism (1)
- Glycosphingolipid biosynthesis - globo series (1)
- Protein export (1)
- Thiamine metabolism (1)