pCMV6-AC-FC Tagged Cloning Vector

CAT#: PS100053

pCMV6-AC-FC, mammalian vector with C-terminal FC tag, 10ug

View all vectors
(tags, promoters, selections)

 Cited in 2 publications.

USD 550.00


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Size
    • 10 ug

Product images

Specifications

Product Data
C-Tag FC
E. coli Selection Ampicillin
Cell Selection Neomycin
Features
  • ORFs cloned in this vector will be expressed in mammalian cells as a tagged protein with a C- terminal murine Fc tag.
  • The Fc-tag encodes the CH2 and CH3 domains of the mouse IgG heavy chain and the hinge region. A fusion protein is comprised of two relatively independent parts connected with a flexible spacer. Fc fusion provides several advantages in protein applications:
    1. Easy purification using protein A or protein G affinity chromatography.
    2. Increased solubility.
    3. Excellent antigen in mouse mAB production without cleavage, as the murine Fc is not antigenic in mice.
  • If the C-terminal tagging interferes with the protein’s function, you can choose the N-terminal Fc-tagging vector, PS100055
  • Download full vector sequence
Schematic of the multiple cloning sites

Citations (2)

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.
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