OPA1 Human siRNA Oligo Duplex (Locus ID 4976)

CAT#: SR303287

OPA1 (Human) - 3 unique 27mer siRNA duplexes - 2 nmol each

Single siRNA in bulk

USD 405.00


Availability*
In Stock

Size
    • 2 nmoles

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Specifications

Product Data
Purity HPLC purified
Quality Control Tested by ESI-MS
Sequences Available with shipment
Stability One year from date of shipment when stored at -20ºC
Shipment Ambient
# of transfections Approximately 330 transfections/2nmol in 24-well plate under optimized conditions (final conc. 10 nM)
Note Single siRNA duplex (10nmol) can be ordered.
Reference Data
RefSeq NM_015560, NM_130831, NM_130832, NM_130833, NM_130834, NM_130835, NM_130836, NM_130837, XM_017006500, XR_001740158, XR_001740159,
Synonyms BERHS; largeG; MGM1; MTDPS14; NPG; NTG
Components OPA1 (Human) - 3 unique 27mer siRNA duplexes - 2 nmol each (Locus ID 4976)
Included - SR30004, Trilencer-27 Universal Scrambled Negative Control siRNA Duplex - 2 nmol
Included - SR30005, RNAse free siRNA Duplex Resuspension Buffer - 2 ml
Summary This gene product is a nuclear-encoded mitochondrial protein with similarity to dynamin-related GTPases. It is a component of the mitochondrial network. Mutations in this gene have been associated with optic atrophy type 1, which is a dominantly inherited optic neuropathy resulting in progressive loss of visual acuity, leading in many cases to legal blindness. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2009].
Performance Guranteed OriGene guarantees that at least two of the three Dicer-Substrate duplexes in the kit will provide at least 70% or more knockdown of the target mRNA when used at 10 nM concentration by quantitative RT-PCR when the TYE-563 fluorescent transfection control duplex (cat# SR30002) indicates that >90% of the cells have been transfected and the HPRT positive control (cat# SR30003) provides 90% knockdown efficiency.

For non-conforming siRNA, requests for replacement product must be made within ninety (90) days from the date of delivery of the siRNA kit. To arrange for a free replacement with newly designed duplexes, please contact Technical Services at techsupport@origene.com. Please provide your data indicating the transfection efficiency and measurement of gene expression knockdown compared to the scrambled siRNA control (quantitative RT-PCR data required).
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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