ABCC1 Human siRNA Oligo Duplex (Locus ID 4363)

CAT#: SR302963

ABCC1 (Human) - 3 unique 27mer siRNA duplexes - 2 nmol each

Single siRNA in bulk

USD 405.00


Availability*
In Stock

Size
    • 2 nmoles

Product images

Specifications

Product Data
Purity HPLC purified
Quality Control Tested by ESI-MS
Sequences Available with shipment
Stability One year from date of shipment when stored at -20ºC
Shipment Ambient
# of transfections Approximately 330 transfections/2nmol in 24-well plate under optimized conditions (final conc. 10 nM)
Note Single siRNA duplex (10nmol) can be ordered.
Reference Data
RefSeq NM_004996, NM_019862, NM_019898, NM_019899, NM_019900, NM_019901, NM_019902, XM_011522497, XM_011522498, XM_017023237, XM_017023238, XM_017023239, XM_017023240, XM_017023241, XM_017023242, XM_017023243,
Synonyms MRP, ABCC, GS-X, MRP1, ABC29, DKFZp781G125, DKFZp686N04233
Components ABCC1 (Human) - 3 unique 27mer siRNA duplexes - 2 nmol each (Locus ID 4363)
Included - SR30004, Trilencer-27 Universal Scrambled Negative Control siRNA Duplex - 2 nmol
Included - SR30005, RNAse free siRNA Duplex Resuspension Buffer - 2 ml
Summary The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra-and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This full transporter is a member of the MRP subfamily which is involved in multi-drug resistance. This protein functions as a multispecific organic anion transporter, with oxidized glutatione, cysteinyl leukotrienes, and activated aflatoxin B1 as substrates. This protein also transports glucuronides and sulfate conjugates of steroid hormones and bile salts. Alternatively spliced variants of this gene have been described but their full-length nature is unknown. [provided by RefSeq, Apr 2012].
Performance Guranteed OriGene guarantees that at least two of the three Dicer-Substrate duplexes in the kit will provide at least 70% or more knockdown of the target mRNA when used at 10 nM concentration by quantitative RT-PCR when the TYE-563 fluorescent transfection control duplex (cat# SR30002) indicates that >90% of the cells have been transfected and the HPRT positive control (cat# SR30003) provides 90% knockdown efficiency.

For non-conforming siRNA, requests for replacement product must be made within ninety (90) days from the date of delivery of the siRNA kit. To arrange for a free replacement with newly designed duplexes, please contact Technical Services at techsupport@origene.com. Please provide your data indicating the transfection efficiency and measurement of gene expression knockdown compared to the scrambled siRNA control (quantitative RT-PCR data required).
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

Citations (1)

Documents