AP2M1 Human shRNA Plasmid Kit (Locus ID 1173)

SKU TR314751

AP2M1 - Human, 4 unique 29mer shRNA constructs in retroviral untagged vector, 5µg of each construct provided

Product Data

• Locus ID: 1173
• Synonyms: AP50; CLAPM1; MRD60; mu2
• Vector: pRS
• E. coli Selection: Ampicillin
• Format: Retroviral plasmids
• Components: AP2M1 - Human, 4 unique 29mer shRNA constructs in retroviral untagged vector(Gene ID = 1173). 5µg purified plasmid DNA per construct; 29-mer scrambled shRNA cassette in pRS Vector, TR30012, included for free.
• RefSeq: BC013796, BC014030, NM_001025205, NM_001311198, NM_004068, NM_001025205.1, NM_004068.1, NM_004068.2, NM_004068.3, BC013796.1, BC014030.1, BC004996, NM_004068.4
• UniProt ID: Q96CW1
• Summary: This gene encodes a subunit of the heterotetrameric coat assembly protein complex 2 (AP2), which belongs to the adaptor complexes medium subunits family. The encoded protein is required for the activity of a vacuolar ATPase, which is responsible for proton pumping occurring in the acidification of endosomes and lysosomes. The encoded protein may also play an important role in regulating the intracellular trafficking and function of CTLA-4 protein. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2015]
• shRNA Design: These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service.
• Shipping: Ambient