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Lgals8 Mouse shRNA Plasmid (Locus ID 56048)

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SKU
TL516910
Lgals8 - Mouse, 4 unique 29mer shRNA constructs in lentiviral GFP vector, 5µg of each construct provided
In Control Promo
  $1,013.00
2 Weeks*

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Specifications
Specifications
Product Data
Locus ID 56048
Synonyms 1200015E08Rik; AI326142; D13Ertd524e; Lgals-8
Vector pGFP-C-shLenti
E. coli Selection Chloramphenicol (34 ug/ml)
Mammalian Cell Selection Puromycin
Format Lentiviral plasmids
Components Lgals8 - Mouse, 4 unique 29mer shRNA constructs in lentiviral GFP vector(Gene ID = 56048). 5µg purified plasmid DNA per construct
29-mer scrambled shRNA cassette in pGFP-C-shLenti Vector, TR30021, included for free.
RefSeq BC040243, NM_001199043, NM_001291055, NM_001291057, NM_001291060, NM_018886, NM_018886.1, NM_018886.2, NM_018886.3, NM_018886.4, NM_018886.5, NM_001291057.1, NM_001291060.1, NM_001199043.1, NM_001291055.1
UniProt ID Q9JL15
Summary Beta-galactoside-binding lectin that acts as a sensor of membrane damage caused by infection and restricts the proliferation of infecting pathogens by targeting them for autophagy. Detects membrane rupture by binding beta-galactoside ligands located on the lumenal side of the endosome membrane; these ligands becoming exposed to the cytoplasm following rupture. Restricts infection by initiating autophagy via interaction with CALCOCO2/NDP52. Required to restrict infection of bacterial invasion such as S.typhimurium. Also required to restrict infection of Picornaviridae viruses. Has a marked preference for 3'-O-sialylated and 3'-O-sulfated glycans.UniProtKB/Swiss-Prot Function
shRNA Design These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service.
Storage Store at -20°C
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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.