Gyltl1b Mouse shRNA Plasmid (Locus ID 228366)

SKU
TL516378
Large2 - Mouse, 4 unique 29mer shRNA constructs in lentiviral GFP vector, 5µg of each construct provided
In Control Promo
  $1,013.00
2 Weeks*
Specifications
Specifications
Product Data
Locus ID 228366
Synonyms 5730485C17Rik; AI891893; Gyltl1b; Largel; mKIAA4105
Vector pGFP-C-shLenti
E. coli Selection Chloramphenicol (34 ug/ml)
Mammalian Cell Selection Puromycin
Format Lentiviral plasmids
Components Large2 - Mouse, 4 unique 29mer shRNA constructs in lentiviral GFP vector(Gene ID = 228366). 5µg purified plasmid DNA per construct
29-mer scrambled shRNA cassette in pGFP-C-shLenti Vector, TR30021, included for free.
RefSeq BC096655, BC116715, NM_001166633, NM_001290773, NM_001290774, NM_001290775, NM_172670, NM_172670.1, NM_172670.2, NM_172670.3, NM_001166633.1, NM_001166633.2, NM_001290775.1, NM_001290774.1, NM_001290773.1, BC004023, BC033922, BC058199
UniProt ID Q5XPT3
Summary Bifunctional glycosyltransferase with both xylosyltransferase and beta-1,3-glucuronyltransferase activities involved in the biosynthesis of the phosphorylated O-mannosyl trisaccharide (N-acetylgalactosamine-beta-3-N-acetylglucosamine-beta-4-(phosphate-6-)mannose), a carbohydrate structure present in alpha-dystroglycan (DAG1). Phosphorylated O-mannosyl trisaccharid is required for binding laminin G-like domain-containing extracellular proteins with high affinity. Elongates the glucuronyl-beta-1,4-xylose-beta disaccharide primer structure by adding repeating units -3-Xylose-alpha-1,3-GlcA-beta-1- to produce a heteropolysaccharide. Has a higher activity toward alpha-dystroglycan than LARGE (PubMed:15958417).UniProtKB/Swiss-Prot Function
shRNA Design These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service.
Storage Store at -20°C
Shipping Ambient
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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.