CD4 Human shRNA Plasmid Kit (Locus ID 920)
SKU
TL314083
CD4 - Human, 4 unique 29mer shRNA constructs in lentiviral GFP vector, 5µg of each construct provided
$1,013.00
2 Weeks*
Specifications
| Product Data | |
| Locus ID | 920 |
|---|---|
| Synonyms | CD4mut; IMD79; OKT4D |
| Vector | pGFP-C-shLenti |
| E. coli Selection | Chloramphenicol (34 ug/ml) |
| Mammalian Cell Selection | Puromycin |
| Format | Lentiviral plasmids |
| Components | CD4 - Human, 4 unique 29mer shRNA constructs in lentiviral GFP vector(Gene ID = 920). 5µg purified plasmid DNA per construct29-mer scrambled shRNA cassette in pGFP-C-shLenti Vector, TR30021, included for free. |
| RefSeq | NM_000616, NM_001195014, NM_001195015, NM_001195016, NM_001195017, NR_036545, NM_000616.1, NM_000616.2, NM_000616.3, NM_000616.4, NM_001195015.1, NM_001195015.2, NM_001195014.1, NM_001195014.2, NM_001195016.1, NM_001195016.2, NM_001195017.1, NM_001195017.2, BC025782, BC025782.1, NM_001195016.3, NM_001195017.3, NM_001195014.3, NM_001195015.3 |
| UniProt ID | P01730 |
| Summary | This gene encodes the CD4 membrane glycoprotein of T lymphocytes. The CD4 antigen acts as a coreceptor with the T-cell receptor on the T lymphocyte to recognize antigens displayed by an antigen presenting cell in the context of class II MHC molecules. The CD4 antigen is also a primary receptor for entry of the human immunodeficiency virus through interactions with the HIV Env gp120 subunit. This gene is expressed not only in T lymphocytes, but also in B cells, macrophages, granulocytes, as well as in various regions of the brain. The protein functions to initiate or augment the early phase of T-cell activation, and may function as an important mediator of indirect neuronal damage in infectious and immune-mediated diseases of the central nervous system. Multiple alternatively spliced transcript variants encoding different isoforms have been identified in this gene. provided by RefSeq, May 2020 |
| shRNA Design | These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service. |
| Storage | Store at -20°C |
| Shipping | Ambient |
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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen
complexities in the preparation of your product. International customers may expect an additional 1-2 weeks
in shipping.