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CMKLR1 Human shRNA Plasmid Kit (Locus ID 1240)

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TL313835
CMKLR1 - Human, 4 unique 29mer shRNA constructs in lentiviral GFP vector, 5µg of each construct provided
In Control Promo
  $1,013.00
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Other products for "CMKLR1 or NM_001142343"

Specifications
Specifications
Product Data
Locus ID 1240
Synonyms CHEMERINR; ChemR23; DEZ; RVER1
Vector pGFP-C-shLenti
E. coli Selection Chloramphenicol (34 ug/ml)
Mammalian Cell Selection Puromycin
Format Lentiviral plasmids
Components CMKLR1 - Human, 4 unique 29mer shRNA constructs in lentiviral GFP vector(Gene ID = 1240). 5µg purified plasmid DNA per construct
29-mer scrambled shRNA cassette in pGFP-C-shLenti Vector, TR30021, included for free.
RefSeq NM_001142343, NM_001142344, NM_001142345, NM_004072, NM_004072.1, NM_004072.2, NM_001142343.1, NM_001142344.1, NM_001142345.1, BC106927, BC106928, NM_001142343.2, NM_001142344.2, NM_004072.3
UniProt ID Q99788
Summary Receptor for the chemoattractant adipokine chemerin/RARRES2 and for the omega-3 fatty acid derived molecule resolvin E1. Interaction with RARRES2 induces activation of intracellular signaling molecules, such as SKY, MAPK1/3 (ERK1/2), MAPK14/P38MAPK and PI3K leading to multifunctional effects, like, reduction of immune responses, enhancing of adipogenesis and angionesis. Resolvin E1 down-regulates cytokine production in macrophages by reducing the activation of MAPK1/3 (ERK1/2) and NF-kappa-B. Positively regulates adipogenesis and adipocyte metabolism. Acts as a coreceptor for several SIV strains (SIVMAC316, SIVMAC239, SIVMACL7E-FR and SIVSM62A), as well as a primary HIV-1 strain (92UG024-2).UniProtKB/Swiss-Prot Function
shRNA Design These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service.
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