CNOT8 Human shRNA Plasmid Kit (Locus ID 9337)
SKU
TL313819
CNOT8 - Human, 4 unique 29mer shRNA constructs in lentiviral GFP vector, 5µg of each construct provided
$1,013.00
2 Weeks*
Specifications
| Product Data | |
| Locus ID | 9337 |
|---|---|
| Synonyms | CAF1; Caf1b; CALIF; hCAF1; POP2 |
| Vector | pGFP-C-shLenti |
| E. coli Selection | Chloramphenicol (34 ug/ml) |
| Mammalian Cell Selection | Puromycin |
| Format | Lentiviral plasmids |
| Components | CNOT8 - Human, 4 unique 29mer shRNA constructs in lentiviral GFP vector(Gene ID = 9337). 5µg purified plasmid DNA per construct29-mer scrambled shRNA cassette in pGFP-C-shLenti Vector, TR30021, included for free. |
| RefSeq | NM_001301073, NM_001301074, NM_001301075, NM_001301077, NM_001301080, NM_001301082, NM_001301083, NM_001301086, NM_004779, NM_004779.1, NM_004779.2, NM_004779.3, NM_004779.4, NM_004779.5, NM_001301086.1, NM_001301075.1, NM_001301077.1, NM_001301080.1, NM_001301082.1, NM_001301083.1, NM_001301074.1, NM_001301073.1, BC017366, BC017366.2, BC093025, NM_001301080.2, NM_001301086.2, NM_001301073.2, NM_001301077.2, NM_001301074.2, NM_004779.6, NM_001301075.2 |
| UniProt ID | Q9UFF9 |
| Summary | Has 3'-5' poly(A) exoribonuclease activity for synthetic poly(A) RNA substrate. Its function seems to be partially redundant with that of CNOT7. Catalytic component of the CCR4-NOT complex which is linked to various cellular processes including bulk mRNA degradation, miRNA-mediated repression, translational repression during translational initiation and general transcription regulation. During miRNA-mediated repression the complex seems also to act as translational repressor during translational initiation. Additional complex functions may be a consequence of its influence on mRNA expression. Associates with members of the BTG family such as TOB1 and BTG2 and is required for their anti-proliferative activity.UniProtKB/Swiss-Prot Function |
| shRNA Design | These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service. |
| Shipping | Ambient |
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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen
complexities in the preparation of your product. International customers may expect an additional 1-2 weeks
in shipping.