COMT Human shRNA Plasmid Kit (Locus ID 1312)
SKU
TL313782
COMT - Human, 4 unique 29mer shRNA constructs in lentiviral GFP vector, 5µg of each construct provided
$1,013.00
In Stock*
Specifications
| Product Data | |
| Locus ID | 1312 |
|---|---|
| Synonyms | HEL-S-98n |
| Vector | pGFP-C-shLenti |
| E. coli Selection | Chloramphenicol (34 ug/ml) |
| Mammalian Cell Selection | Puromycin |
| Format | Lentiviral plasmids |
| Components | COMT - Human, 4 unique 29mer shRNA constructs in lentiviral GFP vector(Gene ID = 1312). 5µg purified plasmid DNA per construct29-mer scrambled shRNA cassette in pGFP-C-shLenti Vector, TR30021, included for free. |
| RefSeq | NM_000754, NM_001135161, NM_001135162, NM_007310, NM_000754.1, NM_000754.2, NM_000754.3, NM_007310.1, NM_001135161.1, NM_001135162.1, BC005867, BC005867.2, BC011935, BC011935.2, BC100018, BC000419, NM_001362828, NM_007310.3, NM_001135161.2, NM_001135162.2, NM_000754.4 |
| UniProt ID | P21964 |
| Summary | Catechol-O-methyltransferase catalyzes the transfer of a methyl group from S-adenosylmethionine to catecholamines, including the neurotransmitters dopamine, epinephrine, and norepinephrine. This O-methylation results in one of the major degradative pathways of the catecholamine transmitters. In addition to its role in the metabolism of endogenous substances, COMT is important in the metabolism of catechol drugs used in the treatment of hypertension, asthma, and Parkinson disease. COMT is found in two forms in tissues, a soluble form (S-COMT) and a membrane-bound form (MB-COMT). The differences between S-COMT and MB-COMT reside within the N-termini. Several transcript variants are formed through the use of alternative translation initiation sites and promoters. provided by RefSeq, Sep 2008 |
| shRNA Design | These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service. |
| Storage | Store at -20°C |
| Shipping | Ambient |
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