Desmocollin 2 (DSC2) Human shRNA Plasmid Kit (Locus ID 1824)
SKU
TL313364
DSC2 - Human, 4 unique 29mer shRNA constructs in lentiviral GFP vector, 5µg of each construct provided
$1,013.00
In Stock*
Specifications
| Product Data | |
| Locus ID | 1824 |
|---|---|
| Synonyms | ARVD11; CDHF2; DG2; DGII/III; DSC3 |
| Vector | pGFP-C-shLenti |
| E. coli Selection | Chloramphenicol (34 ug/ml) |
| Mammalian Cell Selection | Puromycin |
| Format | Lentiviral plasmids |
| Components | DSC2 - Human, 4 unique 29mer shRNA constructs in lentiviral GFP vector(Gene ID = 1824). 5µg purified plasmid DNA per construct29-mer scrambled shRNA cassette in pGFP-C-shLenti Vector, TR30021, included for free. |
| RefSeq | NM_004949, NM_024422, NM_024422.1, NM_024422.2, NM_024422.3, NM_024422.4, NM_004949.1, NM_004949.2, NM_004949.3, NM_004949.4, BC063291, BC063291.1, NM_024422.6, NM_004949.5 |
| UniProt ID | Q02487 |
| Summary | This gene encodes a member of the desmocollin protein subfamily. Desmocollins, along with desmogleins, are cadherin-like transmembrane glycoproteins that are major components of the desmosome. Desmosomes are cell-cell junctions that help resist shearing forces and are found in high concentrations in cells subject to mechanical stress. This gene is found in a cluster with other desmocollin family members on chromosome 18. Mutations in this gene are associated with arrhythmogenic right ventricular dysplasia-11, and reduced protein expression has been described in several types of cancer. Alternative splicing results in multiple transcript variants. provided by RefSeq, Feb 2015 |
| shRNA Design | These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service. |
| Storage | Store at -20°C |
| Shipping | Ambient |
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