ELL Human shRNA Plasmid Kit (Locus ID 8178)

SKU
TL313228
ELL - Human, 4 unique 29mer shRNA constructs in lentiviral GFP vector, 5µg of each construct provided
In Control Promo
  $1,013.00
2 Weeks*
Specifications
Specifications
Product Data
Locus ID 8178
Synonyms C19orf17; ELL1; MEN; PPP1R68
Vector pGFP-C-shLenti
E. coli Selection Chloramphenicol (34 ug/ml)
Mammalian Cell Selection Puromycin
Format Lentiviral plasmids
Components ELL - Human, 4 unique 29mer shRNA constructs in lentiviral GFP vector(Gene ID = 8178). 5µg purified plasmid DNA per construct
29-mer scrambled shRNA cassette in pGFP-C-shLenti Vector, TR30021, included for free.
RefSeq BC010010, NM_006532, NM_006532.1, NM_006532.2, NM_006532.3, BC049195, BC049195.1, BC033673, BC064558, BC108256, NM_006532.4
UniProt ID P55199
Summary Elongation factor component of the super elongation complex (SEC), a complex required to increase the catalytic rate of RNA polymerase II transcription by suppressing transient pausing by the polymerase at multiple sites along the DNA. Elongation factor component of the little elongation complex (LEC), a complex required to regulate small nuclear RNA (snRNA) gene transcription by RNA polymerase II and III (PubMed:22195968, PubMed:23932780). Specifically required for stimulating the elongation step of RNA polymerase II- and III-dependent snRNA gene transcription (PubMed:23932780). ELL also plays an early role before its assembly into in the SEC complex by stabilizing RNA polymerase II recruitment/initiation and entry into the pause site. Required to stabilize the pre-initiation complex and early elongation.UniProtKB/Swiss-Prot Function
shRNA Design These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service.
Storage Store at -20°C
Shipping Ambient
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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.