MBD1 Human shRNA Plasmid Kit (Locus ID 4152)

SKU
TL311559
MBD1 - Human, 4 unique 29mer shRNA constructs in lentiviral GFP vector, 5µg of each construct provided
In Control Promo
  $1,013.00
2 Weeks*
Specifications
Specifications
Product Data
Locus ID 4152
Synonyms CXXC3; PCM1; RFT
Vector pGFP-C-shLenti
E. coli Selection Chloramphenicol (34 ug/ml)
Mammalian Cell Selection Puromycin
Format Lentiviral plasmids
Components MBD1 - Human, 4 unique 29mer shRNA constructs in lentiviral GFP vector(Gene ID = 4152). 5µg purified plasmid DNA per construct
29-mer scrambled shRNA cassette in pGFP-C-shLenti Vector, TR30021, included for free.
RefSeq NM_001204136, NM_001204137, NM_001204138, NM_001204139, NM_001204140, NM_001204141, NM_001204142, NM_001204143, NM_001204151, NM_002384, NM_015844, NM_015845, NM_015846, NM_015847, NM_001323942, NM_001323947, NM_001323949, NM_001323950, NM_001323951, NM_001323952, NM_001323953, NM_001323954, NM_015844.1, NM_015844.2, NM_015846.1, NM_015846.2, NM_015846.3, NM_015845.1, NM_015845.2, NM_015845.3, NM_015847.1, NM_015847.2, NM_015847.3, NM_002384.1, NM_002384.2, NM_001204143.1, NM_001204151.1, NM_001204151.2, NM_001204142.1, NM_001204141.1, NM_001204140.1, NM_001204139.1, NM_001204138.1, NM_001204137.1, NM_001204136.1, BC033242, BC033242.1, BC047353, NM_001204140.2, NM_001204137.2, NM_001204151.3, NM_001204142.2, NM_001204143.2, NM_001204138.2
UniProt ID Q9UIS9
Summary The protein encoded by this gene is a member of a family of nuclear proteins related by the presence of a methyl-CpG binding domain (MBD). These proteins are capable of binding specifically to methylated DNA, and some members can also repress transcription from methylated gene promoters. This protein contains multiple domains: MBD at the N-terminus that functions both in binding to methylated DNA and in protein interactions; several CXXC-type zinc finger domains that mediate binding to non-methylated CpG dinucleotides; transcriptional repression domain (TRD) at the C-terminus that is involved in transcription repression and in protein interactions. Numerous alternatively spliced transcript variants encoding different isoforms have been noted for this gene.provided by RefSeq, Feb 2011
shRNA Design These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service.
Storage Store at -20°C
Shipping Ambient
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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.