RUNX1T1 Human shRNA Plasmid Kit (Locus ID 862)
SKU
TL309684
RUNX1T1 - Human, 4 unique 29mer shRNA constructs in lentiviral GFP vector, 5µg of each construct provided
$1,013.00
2 Weeks*
Specifications
| Product Data | |
| Locus ID | 862 |
|---|---|
| Synonyms | AML1-MTG8; AML1T1; CBFA2T1; CDR; ETO; MTG8; ZMYND2 |
| Vector | pGFP-C-shLenti |
| E. coli Selection | Chloramphenicol (34 ug/ml) |
| Mammalian Cell Selection | Puromycin |
| Format | Lentiviral plasmids |
| Components | RUNX1T1 - Human, 4 unique 29mer shRNA constructs in lentiviral GFP vector(Gene ID = 862). 5µg purified plasmid DNA per construct29-mer scrambled shRNA cassette in pGFP-C-shLenti Vector, TR30021, included for free. |
| RefSeq | NM_001198625, NM_001198626, NM_001198627, NM_001198628, NM_001198629, NM_001198630, NM_001198631, NM_001198632, NM_001198633, NM_001198634, NM_001198679, NM_004349, NM_175634, NM_175635, NM_175636, NM_175636.1, NM_175636.2, NM_004349.1, NM_004349.2, NM_004349.3, NM_175634.1, NM_175634.2, NM_175635.1, NM_175635.2, NM_001198633.1, NM_001198634.1, NM_001198625.1, NM_001198632.1, NM_001198626.1, NM_001198627.1, NM_001198628.1, NM_001198629.1, NM_001198630.1, NM_001198631.1, BC005850, BC067078, BC139783, NM_001198625.2, NM_175634.3, NM_175635.3, NM_001198629.2, NM_001198630.2, NM_001198634.2, NM_004349.4, NM_001198627.2, NM_001198628.2, NM_001198631.2 |
| UniProt ID | Q06455 |
| Summary | This gene encodes a member of the myeloid translocation gene family which interact with DNA-bound transcription factors and recruit a range of corepressors to facilitate transcriptional repression. The t(8;21)(q22;q22) translocation is one of the most frequent karyotypic abnormalities in acute myeloid leukemia. The translocation produces a chimeric gene made up of the 5'-region of the runt-related transcription factor 1 gene fused to the 3'-region of this gene. The chimeric protein is thought to associate with the nuclear corepressor/histone deacetylase complex to block hematopoietic differentiation. Alternative splicing results in multiple transcript variants. provided by RefSeq, Nov 2010 |
| shRNA Design | These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service. |
| Storage | Store at -20°C |
| Shipping | Ambient |
Reviews
Documents
Resources
OriGene AI
Citations
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen
complexities in the preparation of your product. International customers may expect an additional 1-2 weeks
in shipping.