STAT6 Human shRNA Plasmid Kit (Locus ID 6778)
SKU
TL309055
STAT6 - Human, 4 unique 29mer shRNA constructs in lentiviral GFP vector, 5µg of each construct provided
$1,013.00
In Stock*
Specifications
| Product Data | |
| Locus ID | 6778 |
|---|---|
| Synonyms | D12S1644; IL-4-STAT; STAT6B; STAT6C |
| Vector | pGFP-C-shLenti |
| E. coli Selection | Chloramphenicol (34 ug/ml) |
| Mammalian Cell Selection | Puromycin |
| Format | Lentiviral plasmids |
| Components | STAT6 - Human, 4 unique 29mer shRNA constructs in lentiviral GFP vector(Gene ID = 6778). 5µg purified plasmid DNA per construct29-mer scrambled shRNA cassette in pGFP-C-shLenti Vector, TR30021, included for free. |
| RefSeq | NM_001178078, NM_001178079, NM_001178080, NM_001178081, NM_003153, NR_033659, NM_003153.1, NM_003153.2, NM_003153.3, NM_003153.4, NM_001178080.1, NM_001178081.1, NM_001178078.1, NM_001178079.1, BC075852, BC075852.1, BC004973, BC005823, NM_001178079.2, NM_003153.5, NM_001178078.2 |
| UniProt ID | P42226 |
| Summary | The protein encoded by this gene is a member of the STAT family of transcription factors. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein plays a central role in exerting IL4 mediated biological responses. It is found to induce the expression of BCL2L1/BCL-X(L), which is responsible for the anti-apoptotic activity of IL4. Knockout studies in mice suggested the roles of this gene in differentiation of T helper 2 (Th2) cells, expression of cell surface markers, and class switch of immunoglobulins. Alternative splicing results in multiple transcript variants.provided by RefSeq, May 2010 |
| shRNA Design | These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service. |
| Storage | Store at -20°C |
| Shipping | Ambient |
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