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TRIF (TICAM1) Human shRNA Plasmid Kit (Locus ID 148022)

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TL308823
TICAM1 - Human, 4 unique 29mer shRNA constructs in lentiviral GFP vector, 5µg of each construct provided
In Control Promo
  $1,013.00
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Other products for "TRIF or NM_014261"

Specifications
Specifications
Product Data
Locus ID 148022
Synonyms MGC35334; PRVTIRB; TICAM-1; TIR domain-containing adaptor molecule 1; TIR domain containing adaptor inducing interferon-beta; toll-like receptor adaptor molecule 1; TRIF; TRIF, PRVTIRB, TICAM-1, MGC35334
Vector pGFP-C-shLenti
E. coli Selection Chloramphenicol (34 ug/ml)
Mammalian Cell Selection Puromycin
Format Lentiviral plasmids
Components TICAM1 - Human, 4 unique 29mer shRNA constructs in lentiviral GFP vector(Gene ID = 148022). 5µg purified plasmid DNA per construct
29-mer scrambled shRNA cassette in pGFP-C-shLenti Vector, TR30021, included for free.
RefSeq NM_014261, NM_182919, NM_182919.1, NM_182919.2, NM_182919.3, NM_014261.1, BC009860, BC035331, BC136556, BC136557, NM_182919.4
UniProt ID Q8IUC6
Summary This gene encodes an adaptor protein containing a Toll/interleukin-1 receptor (TIR) homology domain, which is an intracellular signaling domain that mediates protein-protein interactions between the Toll-like receptors (TLRs) and signal-transduction components. This protein is involved in native immunity against invading pathogens. It specifically interacts with toll-like receptor 3, but not with other TLRs, and this association mediates dsRNA induction of interferon-beta through activation of nuclear factor kappa-B, during an antiviral immune response. Mutations in this gene are associated with encephalopathy, acute, infection-induced. provided by RefSeq, Jul 2020
shRNA Design These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service.
Storage Store at -20°C
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