TPM1 Human shRNA Plasmid Kit (Locus ID 7168)

SKU
TL308682
TPM1 - Human, 4 unique 29mer shRNA constructs in lentiviral GFP vector, 5µg of each construct provided
In Control Promo
  $1,013.00
2 Weeks*
Specifications
Specifications
Product Data
Locus ID 7168
Synonyms C15orf13; CMD1Y; CMH3; HEL-S-265; HTM-alpha; LVNC9; TMSA
Vector pGFP-C-shLenti
E. coli Selection Chloramphenicol (34 ug/ml)
Mammalian Cell Selection Puromycin
Format Lentiviral plasmids
Components TPM1 - Human, 4 unique 29mer shRNA constructs in lentiviral GFP vector(Gene ID = 7168). 5µg purified plasmid DNA per construct
29-mer scrambled shRNA cassette in pGFP-C-shLenti Vector, TR30021, included for free.
RefSeq NM_000366, NM_001018004, NM_001018005, NM_001018006, NM_001018007, NM_001018008, NM_001018020, NM_001301244, NM_001301289, NM_001330344, NM_001330346, NM_001330351, NM_000366.1, NM_000366.2, NM_000366.3, NM_000366.4, NM_000366.5, NM_001018008.1, NM_001018005.1, NM_001018020.1, NM_001018004.1, NM_001018006.1, NM_001018007.1, NM_001301289.1, NM_001301244.1, BC007433, BC007433.2, BC053545, BC053545.1, BC050473, NM_001365777, NM_001365778, NM_001365779, NM_001365782, NM_001365776, NM_001365780, NM_001365781, NM_001018020.2, NM_001018004.2, NM_001018007.2, NM_001301244.2, NM_001018006.2, NM_001301289.2, NM_001018005.2
UniProt ID P09493
Summary This gene is a member of the tropomyosin family of highly conserved, widely distributed actin-binding proteins involved in the contractile system of striated and smooth muscles and the cytoskeleton of non-muscle cells. Tropomyosin is composed of two alpha-helical chains arranged as a coiled-coil. It is polymerized end to end along the two grooves of actin filaments and provides stability to the filaments. The encoded protein is one type of alpha helical chain that forms the predominant tropomyosin of striated muscle, where it also functions in association with the troponin complex to regulate the calcium-dependent interaction of actin and myosin during muscle contraction. In smooth muscle and non-muscle cells, alternatively spliced transcript variants encoding a range of isoforms have been described. Mutations in this gene are associated with type 3 familial hypertrophic cardiomyopathy. provided by RefSeq, Jul 2008
shRNA Design These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service.
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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.