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APE1 (APEX1) Human shRNA Plasmid Kit (Locus ID 328)

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SKU
TL306647
APEX1 - Human, 4 unique 29mer shRNA constructs in lentiviral GFP vector, 5µg of each construct provided
In Control Promo
  $1,013.00
2 Weeks*

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Other products for "APE1 or NM_001244249"

Specifications
Specifications
Product Data
Locus ID 328
Synonyms APE; APE1; APEN; APEX; APX; HAP1; REF1
Vector pGFP-C-shLenti
E. coli Selection Chloramphenicol (34 ug/ml)
Mammalian Cell Selection Puromycin
Format Lentiviral plasmids
Components APEX1 - Human, 4 unique 29mer shRNA constructs in lentiviral GFP vector(Gene ID = 328). 5µg purified plasmid DNA per construct
29-mer scrambled shRNA cassette in pGFP-C-shLenti Vector, TR30021, included for free.
RefSeq NM_001244249, NM_001641, NM_080648, NM_080649, NM_080648.1, NM_080648.2, NM_001641.1, NM_001641.2, NM_001641.3, NM_080649.1, NM_080649.2, NM_001244249.1, BC004979, BC002338, BC002338.2, BC095428, BC008145, BC019291, NM_080648.3, NM_001244249.2, NM_080649.3, NM_001641.4
UniProt ID P27695
Summary The APEX gene encodes the major AP endonuclease in human cells. It encodes the APEX endonuclease, a DNA repair enzyme with apurinic/apyrimidinic (AP) activity. Such AP activity sites occur frequently in DNA molecules by spontaneous hydrolysis, by DNA damaging agents or by DNA glycosylases that remove specific abnormal bases. The AP sites are the most frequent pre-mutagenic lesions that can prevent normal DNA replication. Splice variants have been found for this gene; all encode the same protein. Disruptions in the biological functions related to APEX are associated with many various malignancies and neurodegenerative diseases.provided by RefSeq, Dec 2019
shRNA Design These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service.
Storage Store at -20°C
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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.