CARD11 Human shRNA Plasmid Kit (Locus ID 84433)

SKU
TL305653
CARD11 - Human, 4 unique 29mer shRNA constructs in lentiviral GFP vector, 5µg of each construct provided
In Control Promo
  $1,013.00
In Stock*
Specifications
Specifications
Product Data
Locus ID 84433
Synonyms BENTA; BIMP3; CARMA1; IMD11; IMD11A; PPBL
Vector pGFP-C-shLenti
E. coli Selection Chloramphenicol (34 ug/ml)
Mammalian Cell Selection Puromycin
Format Lentiviral plasmids
Components CARD11 - Human, 4 unique 29mer shRNA constructs in lentiviral GFP vector(Gene ID = 84433). 5µg purified plasmid DNA per construct
29-mer scrambled shRNA cassette in pGFP-C-shLenti Vector, TR30021, included for free.
RefSeq NM_001324281, NM_032415, NM_032415.1, NM_032415.2, NM_032415.3, NM_032415.4, NM_032415.5, BC111719, NM_032415.7
UniProt ID Q9BXL7
Summary The protein encoded by this gene belongs to the membrane-associated guanylate kinase (MAGUK) family, a class of proteins that functions as molecular scaffolds for the assembly of multiprotein complexes at specialized regions of the plasma membrane. This protein is also a member of the CARD protein family, which is defined by carrying a characteristic caspase-associated recruitment domain (CARD). This protein has a domain structure similar to that of CARD14 protein. The CARD domains of both proteins have been shown to specifically interact with BCL10, a protein known to function as a positive regulator of cell apoptosis and NF-kappaB activation. When expressed in cells, this protein activated NF-kappaB and induced the phosphorylation of BCL10. provided by RefSeq, Jul 2008
shRNA Design These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service.
Storage Store at -20°C
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