CD1E Human shRNA Plasmid Kit (Locus ID 913)

SKU
TL305522
CD1E - Human, 4 unique 29mer shRNA constructs in lentiviral GFP vector, 5µg of each construct provided
In Control Promo
  $1,013.00
2 Weeks*
Specifications
Specifications
Product Data
Locus ID 913
Synonyms CD1A; R2
Vector pGFP-C-shLenti
E. coli Selection Chloramphenicol (34 ug/ml)
Mammalian Cell Selection Puromycin
Format Lentiviral plasmids
Components CD1E - Human, 4 unique 29mer shRNA constructs in lentiviral GFP vector(Gene ID = 913). 5µg purified plasmid DNA per construct
29-mer scrambled shRNA cassette in pGFP-C-shLenti Vector, TR30021, included for free.
RefSeq NM_001042583, NM_001042584, NM_001042585, NM_001042586, NM_001042587, NM_001185107, NM_001185108, NM_001185110, NM_001185112, NM_001185113, NM_001185114, NM_001185115, NM_030893, NM_001042584.1, NM_001042584.2, NM_030893.1, NM_030893.2, NM_030893.3, NM_001042583.1, NM_001042583.2, NM_001042585.1, NM_001042585.2, NM_001042586.1, NM_001042586.2, NM_001042587.1, NM_001042587.2, NM_001185110.1, NM_001185113.1, NM_001185112.1, NM_001185108.1, NM_001185115.1, NM_001185114.1, BC131693, NM_001185113.2, NM_001185110.2, NM_001185107.2, NM_001185115.2, NM_001042583.3, NM_001042585.3, NM_001185108.2, NM_001042587.3, NM_001042584.3, NM_001185112.2, NM_001042586.3, NM_030893.4
UniProt ID P15812
Summary This gene encodes a member of the CD1 family of transmembrane glycoproteins, which are structurally related to the major histocompatibility complex (MHC) proteins and form heterodimers with beta-2-microglobulin. The CD1 proteins mediate the presentation of primarily lipid and glycolipid antigens of self or microbial origin to T cells. The human genome contains five CD1 family genes organized in a cluster on chromosome 1. The CD1 family members are thought to differ in their cellular localization and specificity for particular lipid ligands. The protein encoded by this gene localizes within Golgi compartments, endosomes, and lysosomes, and is cleaved into a stable soluble form. The soluble form is required for the intracellular processing of some glycolipids into a form that can be presented by other CD1 family members. Many alternatively spliced transcript variants encoding different isoforms have been described. Additional transcript variants have been found; however, their biological validity has not been determined. provided by RefSeq, Jun 2010
shRNA Design These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service.
Storage Store at -20°C
Shipping Ambient
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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.