CD46 Human shRNA Plasmid Kit (Locus ID 4179)
SKU
TL305510
CD46 - Human, 4 unique 29mer shRNA constructs in lentiviral GFP vector, 5µg of each construct provided
$1,013.00
2 Weeks*
Specifications
| Product Data | |
| Locus ID | 4179 |
|---|---|
| Synonyms | AHUS2; MCP; MIC10; TLX; TRA2.10 |
| Vector | pGFP-C-shLenti |
| E. coli Selection | Chloramphenicol (34 ug/ml) |
| Mammalian Cell Selection | Puromycin |
| Format | Lentiviral plasmids |
| Components | CD46 - Human, 4 unique 29mer shRNA constructs in lentiviral GFP vector(Gene ID = 4179). 5µg purified plasmid DNA per construct29-mer scrambled shRNA cassette in pGFP-C-shLenti Vector, TR30021, included for free. |
| RefSeq | NM_002389, NM_153826, NM_172350, NM_172351, NM_172352, NM_172353, NM_172354, NM_172355, NM_172356, NM_172357, NM_172358, NM_172359, NM_172360, NM_172361, NM_153826.1, NM_153826.2, NM_153826.3, NM_002389.1, NM_002389.2, NM_002389.3, NM_002389.4, NM_172351.1, NM_172351.2, NM_172354.1, NM_172360.1, NM_172361.1, NM_172361.2, NM_172350.2, NM_172352.1, NM_172352.2, NM_172353.1, NM_172353.2, NM_172356.1, NM_172359.1, NM_172359.2, NM_172358.1, NM_172355.1, NM_172357.1, BC030594, BC030594.2, BC007046, BC026273, NM_153826.4, NM_172353.3, NM_172352.3, NM_172351.3, NM_172356.3, NM_172358.3, NM_172361.3, NM_172350.3, NM_172359.3 |
| UniProt ID | P15529 |
| Summary | The protein encoded by this gene is a type I membrane protein and is a regulatory part of the complement system. The encoded protein has cofactor activity for inactivation of complement components C3b and C4b by serum factor I, which protects the host cell from damage by complement. In addition, the encoded protein can act as a receptor for the Edmonston strain of measles virus, human herpesvirus-6, and type IV pili of pathogenic Neisseria. Finally, the protein encoded by this gene may be involved in the fusion of the spermatozoa with the oocyte during fertilization. Mutations at this locus have been associated with susceptibility to hemolytic uremic syndrome. Alternatively spliced transcript variants encoding different isoforms have been described. provided by RefSeq, Jun 2010 |
| shRNA Design | These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service. |
| Shipping | Ambient |
Reviews
Documents
Resources
OriGene AI
Citations
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen
complexities in the preparation of your product. International customers may expect an additional 1-2 weeks
in shipping.