CD299 (CLEC4M) Human shRNA Plasmid Kit (Locus ID 10332)
SKU
TL305355
CLEC4M - Human, 4 unique 29mer shRNA constructs in lentiviral GFP vector, 5µg of each construct provided
$1,013.00
2 Weeks*
Specifications
| Product Data | |
| Locus ID | 10332 |
|---|---|
| Synonyms | CD209L; CD299; DC-SIGN2; DC-SIGNR; DCSIGNR; HP10347; L-SIGN; LSIGN |
| Vector | pGFP-C-shLenti |
| E. coli Selection | Chloramphenicol (34 ug/ml) |
| Mammalian Cell Selection | Puromycin |
| Format | Lentiviral plasmids |
| Components | CLEC4M - Human, 4 unique 29mer shRNA constructs in lentiviral GFP vector(Gene ID = 10332). 5µg purified plasmid DNA per construct29-mer scrambled shRNA cassette in pGFP-C-shLenti Vector, TR30021, included for free. |
| RefSeq | BC038851, NM_001144904, NM_001144905, NM_001144906, NM_001144907, NM_001144908, NM_001144909, NM_001144910, NM_001144911, NM_014257, NM_214675, NM_214676, NM_214677, NM_214678, NM_214679, NR_026707, NR_026708, NR_026709, NM_014257.1, NM_014257.2, NM_014257.3, NM_014257.4, NM_214675.1, NM_001144904.1, NM_001144905.1, NM_001144906.1, NM_001144907.1, NM_001144908.1, NM_001144909.1, NM_001144910.1, NM_001144911.1, NM_214678.1, NM_214679.1, NM_214677.1, BC038851.1, BC110614, NM_001144910.2, NM_001144911.2, NM_014257.5, NM_001144908.2, NM_001144906.2 |
| UniProt ID | Q9H2X3 |
| Summary | This gene encodes a C-type lectin that functions in cell adhesion and pathogen recognition. This receptor recognizes a wide range of evolutionarily divergent pathogens with a large impact on public health, including tuberculosis mycobacteria, and viruses including Ebola, hepatitis C, HIV-1, influenza A, West Nile virus and the SARS-CoV acute respiratory syndrome coronavirus. The protein is organized into four distinct domains: a C-terminal carbohydrate recognition domain, a flexible tandem-repeat neck domain of variable length, a transmembrane region and an N-terminal cytoplasmic domain involved in internalization. This gene is closely related in terms of both sequence and function to a neighboring gene, CD209 (Gene ID: 30835), also known as DC-SIGN. The two genes differ in viral recognition and expression patterns, with this gene showing high expression in endothelial cells of the liver, lymph node and placenta. Polymorphisms in the tandem repeat neck domain are associated with resistance to SARS infection. provided by RefSeq, May 2020 |
| shRNA Design | These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service. |
| Storage | Store at -20°C |
| Shipping | Ambient |
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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen
complexities in the preparation of your product. International customers may expect an additional 1-2 weeks
in shipping.