Collagen VI (COL6A3) Human shRNA Plasmid Kit (Locus ID 1293)
SKU
TL305287
COL6A3 - Human, 4 unique 29mer shRNA constructs in lentiviral GFP vector, 5µg of each construct provided
$1,013.00
2 Weeks*
Specifications
| Product Data | |
| Locus ID | 1293 |
|---|---|
| Synonyms | BTHLM1; DYT27; UCMD1 |
| Vector | pGFP-C-shLenti |
| E. coli Selection | Chloramphenicol (34 ug/ml) |
| Mammalian Cell Selection | Puromycin |
| Format | Lentiviral plasmids |
| Components | COL6A3 - Human, 4 unique 29mer shRNA constructs in lentiviral GFP vector(Gene ID = 1293). 5µg purified plasmid DNA per construct29-mer scrambled shRNA cassette in pGFP-C-shLenti Vector, TR30021, included for free. |
| RefSeq | NM_004369, NM_057164, NM_057165, NM_057166, NM_057167, NM_057167.1, NM_057167.2, NM_057167.3, NM_057165.1, NM_057165.2, NM_057165.3, NM_057165.4, NM_057164.1, NM_057164.2, NM_057164.3, NM_057164.4, NM_057166.1, NM_057166.2, NM_057166.3, NM_057166.4, NM_004369.2, NM_004369.3, BC033174, BC144595, BC150625, BC171790, BC172233, NM_057164.5, NM_057166.5, NM_057165.5, NM_004369.4 |
| UniProt ID | P12111 |
| Summary | This gene encodes the alpha-3 chain, one of the three alpha chains of type VI collagen, a beaded filament collagen found in most connective tissues. The alpha-3 chain of type VI collagen is much larger than the alpha-1 and -2 chains. This difference in size is largely due to an increase in the number of subdomains, similar to von Willebrand Factor type A domains, that are found in the amino terminal globular domain of all the alpha chains. These domains have been shown to bind extracellular matrix proteins, an interaction that explains the importance of this collagen in organizing matrix components. Mutations in the type VI collagen genes are associated with Bethlem myopathy, a rare autosomal dominant proximal myopathy with early childhood onset. Mutations in this gene are also a cause of Ullrich congenital muscular dystrophy, also referred to as Ullrich scleroatonic muscular dystrophy, an autosomal recessive congenital myopathy that is more severe than Bethlem myopathy. Multiple transcript variants have been identified, but the full-length nature of only some of these variants has been described. provided by RefSeq, Jun 2009 |
| shRNA Design | These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service. |
| Shipping | Ambient |
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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen
complexities in the preparation of your product. International customers may expect an additional 1-2 weeks
in shipping.