DENND1A Human shRNA Plasmid Kit (Locus ID 57706)
SKU
TL305040
DENND1A - Human, 4 unique 29mer shRNA constructs in lentiviral GFP vector, 5µg of each construct provided
$1,013.00
2 Weeks*
Specifications
| Product Data | |
| Locus ID | 57706 |
|---|---|
| Synonyms | FAM31A; KIAA1608 |
| Vector | pGFP-C-shLenti |
| E. coli Selection | Chloramphenicol (34 ug/ml) |
| Mammalian Cell Selection | Puromycin |
| Format | Lentiviral plasmids |
| Components | DENND1A - Human, 4 unique 29mer shRNA constructs in lentiviral GFP vector(Gene ID = 57706). 5µg purified plasmid DNA per construct29-mer scrambled shRNA cassette in pGFP-C-shLenti Vector, TR30021, included for free. |
| RefSeq | NM_020946, NM_024820, NM_001352964, NM_001352965, NM_001352966, NM_001352967, NM_001352968, NR_148208, NM_024820.1, NM_024820.2, NM_020946.1, BC039703, BC039703.1, BC009616, BC028061, NM_024820.3 |
| UniProt ID | Q8TEH3 |
| Summary | Clathrin (see MIM 118955)-mediated endocytosis is a major mechanism for internalization of proteins and lipids. Members of the connecdenn family, such as DENND1A, function as guanine nucleotide exchange factors (GEFs) for the early endosomal small GTPase RAB35 (MIM 604199) and bind to clathrin and clathrin adaptor protein-2 (AP2; see MIM 601024). Thus, connecdenns link RAB35 activation with the clathrin machinery (Marat and McPherson, 2010 PubMed 20154091).supplied by OMIM, Nov 2010 |
| shRNA Design | These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service. |
| Storage | Store at -20°C |
| Shipping | Ambient |
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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen
complexities in the preparation of your product. International customers may expect an additional 1-2 weeks
in shipping.