NEIL2 Human shRNA Plasmid Kit (Locus ID 252969)
SKU
TL302986
NEIL2 - Human, 4 unique 29mer shRNA constructs in lentiviral GFP vector, 5µg of each construct provided
$1,013.00
2 Weeks*
Specifications
| Product Data | |
| Locus ID | 252969 |
|---|---|
| Synonyms | NEH2; NEI2 |
| Vector | pGFP-C-shLenti |
| E. coli Selection | Chloramphenicol (34 ug/ml) |
| Mammalian Cell Selection | Puromycin |
| Format | Lentiviral plasmids |
| Components | NEIL2 - Human, 4 unique 29mer shRNA constructs in lentiviral GFP vector(Gene ID = 252969). 5µg purified plasmid DNA per construct29-mer scrambled shRNA cassette in pGFP-C-shLenti Vector, TR30021, included for free. |
| RefSeq | NM_001135746, NM_001135747, NM_001135748, NM_145043, NM_001349439, NM_001349440, NM_001349441, NM_001349442, NR_146180, NR_146181, NR_146182, NM_145043.1, NM_145043.2, NM_145043.3, NM_001135748.1, NM_001135748.2, NM_001135746.1, NM_001135746.2, NM_001135747.1, NM_001135747.2, BC013952, BC013952.2, BC013964, BC045822, NM_001135747.3, NM_001135748.3, NM_001135746.3 |
| UniProt ID | Q969S2 |
| Summary | This gene encodes a member of the Fpg/Nei family of DNA glycosylases. These glycosylases initiate the first step in base excision repair by cleaving oxidatively damaged bases and introducing a DNA strand break via their abasic site lyase activity. This enzyme is primarily associated with DNA repair during transcription and acts prefentially on cytosine-derived lesions, particularly 5-hydroxyuracil and 5-hydroxycytosine. It contains an N-terminal catalytic domain, a hinge region, and a C-terminal DNA-binding domain with helix-two-turn-helix and zinc finger motifs. This enzyme interacts with the X-ray cross complementing factor 1 scaffold protein as part of a multi-protein DNA repair complex. A pseudogene of this gene has been identified. provided by RefSeq, Mar 2017 |
| shRNA Design | These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service. |
| Storage | Store at -20°C |
| Shipping | Ambient |
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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen
complexities in the preparation of your product. International customers may expect an additional 1-2 weeks
in shipping.