MTH1 (NUDT1) Human shRNA Plasmid Kit (Locus ID 4521)
SKU
TL302860
NUDT1 - Human, 4 unique 29mer shRNA constructs in lentiviral GFP vector, 5µg of each construct provided
$1,013.00
In Stock*
Specifications
| Product Data | |
| Locus ID | 4521 |
|---|---|
| Synonyms | MTH1 |
| Vector | pGFP-C-shLenti |
| E. coli Selection | Chloramphenicol (34 ug/ml) |
| Mammalian Cell Selection | Puromycin |
| Format | Lentiviral plasmids |
| Components | NUDT1 - Human, 4 unique 29mer shRNA constructs in lentiviral GFP vector(Gene ID = 4521). 5µg purified plasmid DNA per construct29-mer scrambled shRNA cassette in pGFP-C-shLenti Vector, TR30021, included for free. |
| RefSeq | NM_002452, NM_198948, NM_198949, NM_198950, NM_198952, NM_198953, NM_198954, NM_198952.1, NM_002452.1, NM_002452.2, NM_002452.3, NM_198948.1, NM_198949.1, NM_198950.1, NM_198953.1, NM_198954.1, BC014618, BC014618.2, BC051375, BC051375.1, BC040144, BC022818, BC065367, BM927392, NM_001367553, NM_001367554, NM_001367555, NR_160264 |
| UniProt ID | P36639 |
| Summary | Misincorporation of oxidized nucleoside triphosphates into DNA/RNA during replication and transcription can cause mutations that may result in carcinogenesis or neurodegeneration. The protein encoded by this gene is an enzyme that hydrolyzes oxidized purine nucleoside triphosphates, such as 8-oxo-dGTP, 8-oxo-dATP, 2-hydroxy-dATP, and 2-hydroxy rATP, to monophosphates, thereby preventing misincorporation. The encoded protein is localized mainly in the cytoplasm, with some in the mitochondria, suggesting that it is involved in the sanitization of nucleotide pools both for nuclear and mitochondrial genomes. Several alternatively spliced transcript variants, some of which encode distinct isoforms, have been identified. Additional variants have been observed, but their full-length natures have not been determined. A rare single-nucleotide polymorphism that results in the production of an additional, longer isoform (p26) has been described. provided by RefSeq, Dec 2018 |
| shRNA Design | These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service. |
| Shipping | Ambient |
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