Pyruvate Kinase (PKLR) Human shRNA Plasmid Kit (Locus ID 5313)

SKU
TL302463
PKLR - Human, 4 unique 29mer shRNA constructs in lentiviral GFP vector, 5µg of each construct provided
In Control Promo
  $1,013.00
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Specifications
Specifications
Product Data
Locus ID 5313
Synonyms PK1; PKL; PKRL; RPK
Vector pGFP-C-shLenti
E. coli Selection Chloramphenicol (34 ug/ml)
Mammalian Cell Selection Puromycin
Format Lentiviral plasmids
Components PKLR - Human, 4 unique 29mer shRNA constructs in lentiviral GFP vector(Gene ID = 5313). 5µg purified plasmid DNA per construct
29-mer scrambled shRNA cassette in pGFP-C-shLenti Vector, TR30021, included for free.
RefSeq NM_000298, NM_181871, NM_000298.1, NM_000298.2, NM_000298.4, NM_000298.5, NM_181871.1, NM_181871.2, NM_181871.3, BC025737, BC025737.1, NM_181871.4
UniProt ID P30613
Summary The protein encoded by this gene is a pyruvate kinase that catalyzes the transphosphorylation of phohsphoenolpyruvate into pyruvate and ATP, which is the rate-limiting step of glycolysis. Defects in this enzyme, due to gene mutations or genetic variations, are the common cause of chronic hereditary nonspherocytic hemolytic anemia (CNSHA or HNSHA). Multiple transcript variants encoding different isoforms have been found for this gene. provided by RefSeq, Jul 2008
shRNA Design These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service.
Storage Store at -20°C
Shipping Ambient
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