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SERINC5 Human shRNA Plasmid Kit (Locus ID 256987)

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TL301764
SERINC5 - Human, 4 unique 29mer shRNA constructs in lentiviral GFP vector, 5µg of each construct provided
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  $1,013.00
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Specifications
Specifications
Product Data
Locus ID 256987
Synonyms C5orf12; TPO1
Vector pGFP-C-shLenti
E. coli Selection Chloramphenicol (34 ug/ml)
Mammalian Cell Selection Puromycin
Format Lentiviral plasmids
Components SERINC5 - Human, 4 unique 29mer shRNA constructs in lentiviral GFP vector(Gene ID = 256987). 5µg purified plasmid DNA per construct
29-mer scrambled shRNA cassette in pGFP-C-shLenti Vector, TR30021, included for free.
RefSeq NM_001174071, NM_001174072, NM_178276, NR_126060, NR_126061, NM_178276.1, NM_178276.2, NM_178276.3, NM_178276.4, NM_178276.5, NM_178276.6, NM_001174071.1, NM_001174071.2, NM_001174072.1, NM_001174072.2, BC101280, BC101281, BC101282, BC101283, NM_001174071.3, NM_001174072.3, NM_178276.7
UniProt ID Q86VE9
Summary Restriction factor required to restrict infectivity of lentiviruses, such as HIV-1: acts by inhibiting an early step of viral infection. Impairs the penetration of the viral particle into the cytoplasm (PubMed:26416733, PubMed:26416734). Enhances the incorporation of serine into phosphatidylserine and sphingolipids. May play a role in providing serine molecules for the formation of myelin glycosphingolipids in oligodendrocytes (By similarity).UniProtKB/Swiss-Prot Function
shRNA Design These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service.
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