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SGOL2 (SGO2) Human shRNA Plasmid Kit (Locus ID 151246)

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SKU
TL301730
SGO2 - Human, 4 unique 29mer shRNA constructs in lentiviral GFP vector, 5µg of each construct provided
  $1,013.00
2 Weeks*

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Other products for "SGOL2 or NM_001160033"

Specifications
Specifications
Product Data
Locus ID 151246
Synonyms SGOL2; TRIPIN
Vector pGFP-C-shLenti
E. coli Selection Chloramphenicol (34 ug/ml)
Format Lentiviral plasmids
Components SGO2 - Human, 4 unique 29mer shRNA constructs in lentiviral GFP vector(Gene ID = 151246). 5µg purified plasmid DNA per construct
29-mer scrambled shRNA cassette in pGFP-C-shLenti Vector, TR30021, included for free.
RefSeq NM_001160033, NM_001160046, NM_152524, NM_152524.1, NM_152524.2, NM_152524.3, NM_152524.4, NM_152524.5, NM_001160033.1, NM_001160046.1, BC092412, BC092412.1, BC004567, BC035764, BC048349, BC110583, NM_152524.6
UniProt ID Q562F6
Summary Cooperates with PPP2CA to protect centromeric cohesin from separase-mediated cleavage in oocytes specifically during meiosis I. Has a crucial role in protecting REC8 at centromeres from cleavage by separase. During meiosis, protects centromeric cohesion complexes until metaphase II/anaphase II transition, preventing premature release of meiosis-specific REC8 cohesin complexes from anaphase I centromeres. Is thus essential for an accurate gametogenesis. May act by targeting PPP2CA to centromeres, thus leading to cohesin dephosphorylation (By similarity). Essential for recruiting KIF2C to the inner centromere and for correcting defective kinetochore attachments. Involved in centromeric enrichment of AUKRB in prometaphase.UniProtKB/Swiss-Prot Function
shRNA Design These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service.
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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.