Staufen (STAU1) Human shRNA Plasmid Kit (Locus ID 6780)

SKU
TL301346
STAU1 - Human, 4 unique 29mer shRNA constructs in lentiviral GFP vector, 5µg of each construct provided
  $1,013.00
In Stock*
Specifications
Specifications
Product Data
Locus ID 6780
Synonyms PPP1R150; STAU
Vector pGFP-C-shLenti
E. coli Selection Chloramphenicol (34 ug/ml)
Format Lentiviral plasmids
Components STAU1 - Human, 4 unique 29mer shRNA constructs in lentiviral GFP vector(Gene ID = 6780). 5µg purified plasmid DNA per construct
29-mer scrambled shRNA cassette in pGFP-C-shLenti Vector, TR30021, included for free.
RefSeq NM_001037328, NM_001319134, NM_001319135, NM_004602, NM_017452, NM_017453, NM_017454, NM_001322927, NM_001322928, NM_001322929, NM_001322930, NM_001322931, NM_001322932, NM_001322933, NM_017453.1, NM_017453.2, NM_017453.3, NM_004602.1, NM_004602.2, NM_004602.3, NM_017454.1, NM_017454.2, NM_017454.3, NM_017452.1, NM_017452.2, NM_017452.3, NM_001037328.1, NM_001037328.2, BC050432, BC050432.1, BC095397, BC095397.1, BC000830, BC001893, BC007532, BC010169, NM_017453.4
UniProt ID O95793
Summary Staufen is a member of the family of double-stranded RNA (dsRNA)-binding proteins involved in the transport and/or localization of mRNAs to different subcellular compartments and/or organelles. These proteins are characterized by the presence of multiple dsRNA-binding domains which are required to bind RNAs having double-stranded secondary structures. The human homologue of staufen encoded by STAU, in addition contains a microtubule- binding domain similar to that of microtubule-associated protein 1B, and binds tubulin. The STAU gene product has been shown to be present in the cytoplasm in association with the rough endoplasmic reticulum (RER), implicating this protein in the transport of mRNA via the microtubule network to the RER, the site of translation. provided by RefSeq, Apr 2020
shRNA Design These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service.
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