Tropomyosin 3 (TPM3) Human shRNA Plasmid Kit (Locus ID 7170)

SKU
TL300879
TPM3 - Human, 4 unique 29mer shRNA constructs in lentiviral GFP vector, 5µg of each construct provided
  $1,013.00
In Stock*
Specifications
Specifications
Product Data
Locus ID 7170
Synonyms CAPM1; CFTD; HEL-189; HEL-S-82p; hscp30; NEM1; OK/SW-cl.5; TM-5; TM3; TM5; TM30; TM30nm; TPM3nu; TPMsk3; TRK
Vector pGFP-C-shLenti
E. coli Selection Chloramphenicol (34 ug/ml)
Format Lentiviral plasmids
Components TPM3 - Human, 4 unique 29mer shRNA constructs in lentiviral GFP vector(Gene ID = 7170). 5µg purified plasmid DNA per construct
29-mer scrambled shRNA cassette in pGFP-C-shLenti Vector, TR30021, included for free.
RefSeq NM_001043351, NM_001043352, NM_001043353, NM_001278188, NM_001278189, NM_001278190, NM_001278191, NM_152263, NM_153649, NR_103460, NR_103461, NM_001349679, NM_152263.1, NM_152263.2, NM_152263.3, NM_153649.1, NM_153649.2, NM_153649.3, NM_001043351.1, NM_001043353.1, NM_001043352.1, NM_001278191.1, NM_001278188.1, NM_001278190.1, NM_001278189.1, BC008425, BC008425.1, BC072428, BC072428.1, BC000771, BC008407, BC015403, BC017195, BC050470, BC062740, BC073144, BM674269, BM674651, NM_001364679, NM_001364681, NM_001364683, NM_001364680, NM_001364682, NM_001278189.2, NM_153649.4, NM_001043352.2, NM_001278188.2, NM_001278191.2, NM_001043353.2, NM_001043351.2, NM_152263.4
UniProt ID P06753
Summary This gene encodes a member of the tropomyosin family of actin-binding proteins. Tropomyosins are dimers of coiled-coil proteins that provide stability to actin filaments and regulate access of other actin-binding proteins. Mutations in this gene result in autosomal dominant nemaline myopathy and other muscle disorders. This locus is involved in translocations with other loci, including anaplastic lymphoma receptor tyrosine kinase (ALK) and neurotrophic tyrosine kinase receptor type 1 (NTRK1), which result in the formation of fusion proteins that act as oncogenes. There are numerous pseudogenes for this gene on different chromosomes. Alternative splicing results in multiple transcript variants. provided by RefSeq, May 2013
shRNA Design These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service.
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