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UBE1C (UBA3) Human shRNA Plasmid Kit (Locus ID 9039)

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SKU
TL300705
UBA3 - Human, 4 unique 29mer shRNA constructs in lentiviral GFP vector, 5µg of each construct provided
  $1,013.00
2 Weeks*

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Specifications
Specifications
Product Data
Locus ID 9039
Synonyms hUBA3; NAE2; UBE1C
Vector pGFP-C-shLenti
E. coli Selection Chloramphenicol (34 ug/ml)
Format Lentiviral plasmids
Components UBA3 - Human, 4 unique 29mer shRNA constructs in lentiviral GFP vector(Gene ID = 9039). 5µg purified plasmid DNA per construct
29-mer scrambled shRNA cassette in pGFP-C-shLenti Vector, TR30021, included for free.
RefSeq NM_003968, NM_198195, NM_198197, NM_003968.1, NM_003968.2, NM_003968.3, NM_198195.1, NM_198197.1, BC022853, BC022853.1, NM_001363861, NM_198195.2, NM_003968.4
UniProt ID Q8TBC4
Summary The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. This gene encodes a member of the E1 ubiquitin-activating enzyme family. The encoded enzyme associates with AppBp1, an amyloid beta precursor protein binding protein, to form a heterodimer, and then the enzyme complex activates NEDD8, a ubiquitin-like protein, which regulates cell division, signaling and embryogenesis. Multiple alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. provided by RefSeq, Jul 2008
shRNA Design These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service.
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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.