Munc 13 4 (UNC13D) Human shRNA Plasmid Kit (Locus ID 201294)

SKU
TL300652
UNC13D - Human, 4 unique 29mer shRNA constructs in lentiviral GFP vector, 5µg of each construct provided
  $1,013.00
2 Weeks*
Specifications
Specifications
Product Data
Locus ID 201294
Synonyms FHL3; HLH3; HPLH3; Munc13-4
Vector pGFP-C-shLenti
E. coli Selection Chloramphenicol (34 ug/ml)
Format Lentiviral plasmids
Components UNC13D - Human, 4 unique 29mer shRNA constructs in lentiviral GFP vector(Gene ID = 201294). 5µg purified plasmid DNA per construct
29-mer scrambled shRNA cassette in pGFP-C-shLenti Vector, TR30021, included for free.
RefSeq NM_199242, NM_199242.1, NM_199242.2, BC067084, BC024740, NM_199242.3
UniProt ID Q70J99
Summary This gene encodes a protein that is a member of the UNC13 family, containing similar domain structure as other family members but lacking an N-terminal phorbol ester-binding C1 domain present in other Munc13 proteins. The protein appears to play a role in vesicle maturation during exocytosis and is involved in regulation of cytolytic granules secretion. Mutations in this gene are associated with familial hemophagocytic lymphohistiocytosis type 3, a genetically heterogeneous, rare autosomal recessive disorder. provided by RefSeq, Jul 2008
shRNA Design These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service.
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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.