UPF3A Human shRNA Plasmid Kit (Locus ID 65110)
SKU
TL300640
UPF3A - Human, 4 unique 29mer shRNA constructs in lentiviral GFP vector, 5µg of each construct provided
$1,013.00
2 Weeks*
Specifications
| Product Data | |
| Locus ID | 65110 |
|---|---|
| Synonyms | HUPF3A; RENT3A; UPF3 |
| Vector | pGFP-C-shLenti |
| E. coli Selection | Chloramphenicol (34 ug/ml) |
| Format | Lentiviral plasmids |
| Components | UPF3A - Human, 4 unique 29mer shRNA constructs in lentiviral GFP vector(Gene ID = 65110). 5µg purified plasmid DNA per construct29-mer scrambled shRNA cassette in pGFP-C-shLenti Vector, TR30021, included for free. |
| RefSeq | NM_023011, NM_080687, NM_001353644, NM_001353645, NM_001353646, NM_001353647, NM_001353648, NM_001353649, NM_001353650, NM_001353651, NM_001353652, NR_148482, NR_148483, NR_148484, NR_148485, NR_148486, NR_148487, NR_148488, NR_148489, NR_148490, NR_148491, NR_148492, NR_148493, NR_148494, NR_148495, NR_148496, NM_080687.1, NM_080687.2, NM_023011.1, NM_023011.2, NM_023011.3, BC023569, BC023569.1, BC008694, BC047735, NM_080687.3, NM_023011.4 |
| UniProt ID | Q9H1J1 |
| Summary | This gene encodes a protein that is part of a post-splicing multiprotein complex involved in both mRNA nuclear export and mRNA surveillance. The encoded protein is one of two functional homologs to yeast Upf3p. mRNA surveillance detects exported mRNAs with truncated open reading frames and initiates nonsense-mediated mRNA decay (NMD). When translation ends upstream from the last exon-exon junction, this triggers NMD to degrade mRNAs containing premature stop codons. This protein binds to the mRNA and remains bound after nuclear export, acting as a nucleocytoplasmic shuttling protein. It forms with Y14 a complex that binds specifically 20 nt upstream of exon-exon junctions. This gene is located on the long arm of chromosome 13. Several splice variants encoding different isoforms have been found for this gene. provided by RefSeq, Jul 2017 |
| shRNA Design | These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service. |
| Shipping | Ambient |
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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen
complexities in the preparation of your product. International customers may expect an additional 1-2 weeks
in shipping.