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WDR79 (WRAP53) Human shRNA Plasmid Kit (Locus ID 55135)

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SKU
TL300472
WRAP53 - Human, 4 unique 29mer shRNA constructs in lentiviral GFP vector, 5µg of each construct provided
  $1,013.00
2 Weeks*

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Other products for "WDR79 or NM_001143990"

Specifications
Specifications
Product Data
Locus ID 55135
Synonyms DKCB3; TCAB1; WDR79
Vector pGFP-C-shLenti
E. coli Selection Chloramphenicol (34 ug/ml)
Format Lentiviral plasmids
Components WRAP53 - Human, 4 unique 29mer shRNA constructs in lentiviral GFP vector(Gene ID = 55135). 5µg purified plasmid DNA per construct
29-mer scrambled shRNA cassette in pGFP-C-shLenti Vector, TR30021, included for free.
RefSeq NM_001143990, NM_001143991, NM_001143992, NM_018081, NM_018081.1, NM_018081.2, NM_001143990.1, NM_001143991.1, NM_001143992.1, BC002336, BC002336.2, NM_001143992.2, NM_001143991.2
UniProt ID Q9BUR4
Summary This gene encodes an essential component of the telomerase holoenzyme complex, a ribonucleoprotein complex required for telomere synthesis. This protein is enriched in Cajal bodies, nuclear sites of RNP processing that are important for telomerase function. It interacts with dyskerin, TERT and TERC, other components of active telomerase, and with small Cajal body RNAs (scaRNAs), which are involved in modifying splicing RNAs. This mRNA also functions as a p53 antisense transcript, that regulates endogenous p53 mRNA levels and further induction of p53 protein by targeting the 5' untranslated region of p53 mRNA. Alternatively spliced transcript variants which differ only in the 5' UTR have been found for this gene. provided by RefSeq, Mar 2011
shRNA Design These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service.
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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.