XRCC4 Human shRNA Plasmid Kit (Locus ID 7518)

SKU
TL300422
XRCC4 - Human, 4 unique 29mer shRNA constructs in lentiviral GFP vector, 5µg of each construct provided
  $1,013.00
2 Weeks*
Specifications
Specifications
Product Data
Locus ID 7518
Synonyms SSMED
Vector pGFP-C-shLenti
E. coli Selection Chloramphenicol (34 ug/ml)
Format Lentiviral plasmids
Components XRCC4 - Human, 4 unique 29mer shRNA constructs in lentiviral GFP vector(Gene ID = 7518). 5µg purified plasmid DNA per construct
29-mer scrambled shRNA cassette in pGFP-C-shLenti Vector, TR30021, included for free.
RefSeq BC005259, NM_001318012, NM_001318013, NM_003401, NM_022406, NM_022550, NM_022406.1, NM_022406.2, NM_022406.3, NM_003401.1, NM_003401.2, NM_003401.3, NM_003401.4, NM_022550.1, NM_022550.2, NM_022550.3, BC005259.1, BC016314, BC016314.1, BC010655, NM_022406.4, NM_003401.5
UniProt ID Q13426
Summary The protein encoded by this gene functions together with DNA ligase IV and the DNA-dependent protein kinase in the repair of DNA double-strand breaks. This protein plays a role in both non-homologous end joining and the completion of V(D)J recombination. Mutations in this gene can cause short stature, microcephaly, and endocrine dysfunction (SSMED). Alternate transcript variants such as NM_022406 are unlikely to be expressed in some individuals due to a polymorphism (rs1805377) in the last splice acceptor site. provided by RefSeq, Oct 2019
shRNA Design These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service.
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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.