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Gorasp2 Mouse shRNA Plasmid (Locus ID 70231)

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TG517113
Gorasp2 - Mouse, 4 unique 29mer shRNA constructs in retroviral GFP vector, 5µg of each construct provided
  $883.00
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Specifications
Specifications
Product Data
Locus ID 70231
Synonyms 0610011A07Rik; 2410043M02Rik; 5730520M13Rik; 9430094F20Rik; AW552058
Vector pGFP-V-RS
E. coli Selection Kanamycin
Format Retroviral plasmids
Components Gorasp2 - Mouse, 4 unique 29mer shRNA constructs in retroviral GFP vector(Gene ID = 70231). 5µg purified plasmid DNA per construct
29-mer scrambled shRNA cassette in pGFP-V-RS Vector, TR30013, included for free.
RefSeq BC005600, BC016455, NM_027352, NR_027343, NM_027352.1, NM_027352.2, NM_027352.3, NM_027352.4, BC007468, BC024982
UniProt ID Q99JX3
Summary Plays a role in assembly and membrane stacking of the Golgi cisternae, and in the process by which Golgi stacks reform after breakdown during mitosis and meiosis (PubMed:28617811). May regulate the intracellular transport and presentation of a defined set of transmembrane proteins, such as transmembrane TGFA (By similarity). Required for normal acrosome formation during spermiogenesis and normal male fertility, probably by promoting colocalization of JAM2 and JAM3 at contact sites between germ cells and Sertoli cells (PubMed:28617811). Mediates ER stress-induced unconventional (ER/Golgi-independent) trafficking of core-glycosylated CFTR to cell membrane (By similarity).UniProtKB/Swiss-Prot Function
shRNA Design These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service.
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