Iqgap1 Mouse shRNA Plasmid (Locus ID 29875)

SKU
TG512619
Iqgap1 - Mouse, 4 unique 29mer shRNA constructs in retroviral GFP vector, 5µg of each construct provided
  $883.00
In Stock*
Specifications
Specifications
Product Data
Locus ID 29875
Synonyms AA682088; D7Ertd237e; D7Ertd257e; mKIAA0051
Vector pGFP-V-RS
E. coli Selection Kanamycin
Format Retroviral plasmids
Components Iqgap1 - Mouse, 4 unique 29mer shRNA constructs in retroviral GFP vector(Gene ID = 29875). 5µg purified plasmid DNA per construct
29-mer scrambled shRNA cassette in pGFP-V-RS Vector, TR30013, included for free.
RefSeq BC046385, NM_016721, NM_016721.1, NM_016721.2, BC022105, BC037685
UniProt ID Q9JKF1
Summary Plays a crucial role in regulating the dynamics and assembly of the actin cytoskeleton. Binds to activated CDC42 but does not stimulate its GTPase activity (PubMed:16968698). It associates with calmodulin. Could serve as an assembly scaffold for the organization of a multimolecular complex that would interface incoming signals to the reorganization of the actin cytoskeleton at the plasma membrane. May promote neurite outgrowth. May play a possible role in cell cycle regulation by contributing to cell cycle progression after DNA replication arrest.UniProtKB/Swiss-Prot Function
shRNA Design These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service.
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