Wnt1 Mouse shRNA Plasmid (Locus ID 22408)

SKU
TG512577
Wnt1 - Mouse, 4 unique 29mer shRNA constructs in retroviral GFP vector, 5µg of each construct provided
  $883.00
In Stock*
Specifications
Specifications
Product Data
Locus ID 22408
Synonyms Int-1; sw; swaying; Wnt-1
Vector pGFP-V-RS
E. coli Selection Kanamycin
Format Retroviral plasmids
Components Wnt1 - Mouse, 4 unique 29mer shRNA constructs in retroviral GFP vector(Gene ID = 22408). 5µg purified plasmid DNA per construct
29-mer scrambled shRNA cassette in pGFP-V-RS Vector, TR30013, included for free.
RefSeq BC005449, NM_021279, NM_021279.2, NM_021279.3, NM_021279.4
UniProt ID P04426
Summary Ligand for members of the frizzled family of seven transmembrane receptors. Acts in the canonical Wnt signaling pathway by promoting beta-catenin-dependent transcriptional activation (By similarity). In some developmental processes, is also a ligand for the coreceptor RYK, thus triggering Wnt signaling (PubMed:15454084, PubMed:16116452). Plays an essential role in the development of the embryonic brain and central nervous system (CNS) (PubMed:2202907, PubMed:16116452). Has a role in osteoblast function, bone development and bone homeostasis (By similarity).UniProtKB/Swiss-Prot Function
shRNA Design These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service.
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